Research workbench
AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2 (Q13416)
Analyse AlphaFold monomer V2.0 prediction for origin recognition complex subunit 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q13416
- Type
- protein
- Length
- 577 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5A7632cD68306eB5715122da5B344c6126FB602A
- Molecule
- Origin recognition complex subunit 2
- UniProt
- Q13416
- Pockets
- 6 · best druggability 0.52
Structure
1 distinct chain · 36% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Origin recognition complex subunit 2 | protein | 577 | 36% helix, 7% strand | Q13416 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 116 | 0.52 | 0.82 | 20 | empty |
| 2 | 175 | 0.49 | 0.77 | 18 | empty |
| 3 | 108 | 0.45 | 0.78 | 18 | empty |
| 4 | 76 | 0.40 | 0.79 | 12 | empty |
| 5 | 116 | 0.35 | 0.72 | 19 | empty |
Compared structures
- 7JPP · Orc-O2WH: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC1 aaa+ domain · an experimental structure of the same protein · chain A against B, TM-score 0.37
- 7JPR · Orc-open: human origin recognition complex (orc) in an open conformation · an experimental structure of the same protein · chain A against B, TM-score 0.37
- 7CTF · Human origin recognition complex 1-5 state II · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 7JPQ · Orc-O2-5: human origin recognition complex (orc) with subunits 2,3,4,5 · an experimental structure of the same protein · chain A against B, TM-score 0.36
- 7JPO · Orc-O1AAA: human origin recognition complex (orc) with DYNAMIC/UNRESOLVED ORC2 wh · an experimental structure of the same protein · chain A against B, TM-score 0.35
- 7JPO · ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH · an experimental structure of the same protein · chain A against B, TM-score 0.35
- 7CTE · Human origin recognition complex, ORC2-5 · an experimental structure of the same protein · chain A against B, TM-score 0.35
- 7CTG · Human origin recognition complex, ORC1-5 state I · an experimental structure of the same protein · chain A against B, TM-score 0.35
- 7JPS · Orc-DNA: human origin recognition complex (orc) with DNA bound in the core · an experimental structure of the same protein · chain A against B, TM-score 0.34
- 5UJM · Structure of the active form of human origin recognition complex and its ATPase motor… · an experimental structure of the same protein · chain A against B, TM-score 0.32
- 8S0C · H. sapiens ORC1-5 bound to double stranded DNA as part of the MCM-ORC complex · an experimental structure of the same protein · chain A against B, TM-score 0.32
- 8S0D · H. sapiens MCM bound to double stranded DNA and ORC1-6 · an experimental structure of the same protein · chain A against B, TM-score 0.32
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13416
- Elsewhere: UniProt Q13416 · AlphaFold DB Q13416
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