Research workbench
AlphaFold monomer V2.0 prediction for gator complex protein NPRL2 (Q8WTW4)
Analyse AlphaFold monomer V2.0 prediction for gator complex protein NPRL2 (Q8WTW4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8WTW4
- Type
- protein
- Length
- 380 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xe76b3F28d48eB037bFBabB880119B8b2f3E26Fb5
- Molecule
- Gator complex protein NPRL2
- UniProt
- Q8WTW4
- Pockets
- 4 · best druggability 0.38
Structure
1 distinct chain · 42% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gator complex protein NPRL2 | protein | 380 | 42% helix, 24% strand | Q8WTW4 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 80 | 0.38 | 0.77 | 18 | empty |
| 2 | 63 | 0.37 | 0.78 | 14 | empty |
| 3 | 82 | 0.34 | 0.75 | 16 | empty |
| 4 | 95 | 0.33 | 0.73 | 16 | empty |
Compared structures
- 7T3A · GATOR1-RAG-RAGULATOR - Inhibitory Complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 7T3A · GATOR1-rag-ragulator - inhibitory complex · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 8FW5 · Chimeric HsGATOR1-SpGtr-SpLam complex · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 7T3C · GATOR1-rag-ragulator - dual complex · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 7T3C · GATOR1-RAG-RAGULATOR - Dual Complex · an experimental structure of the same protein · chain A against B, TM-score 0.81
- 7T3B · GATOR1-RAG-RAGULATOR - GAP Complex · an experimental structure of the same protein · chain A against B, TM-score 0.80
- 7T3B · GATOR1-rag-ragulator - gap complex · an experimental structure of the same protein · chain A against B, TM-score 0.80
- 6CES · Cryo-EM structure of GATOR1-rag · an experimental structure of the same protein · chain A against N, TM-score 0.62
- 6CES · Cryo-EM structure of GATOR1-RAG · an experimental structure of the same protein · chain A against N, TM-score 0.62
- 6CET · Cryo-EM structure of GATOR1 · an experimental structure of the same protein · chain A against N, TM-score 0.61
- 6CET · Cryo-EM structure of GATOR1 · an experimental structure of the same protein · chain A against N, TM-score 0.61
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WTW4
- Elsewhere: UniProt Q8WTW4 · AlphaFold DB Q8WTW4
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