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UniProt Q9Y7G6

RNA-dependent RNA polymerase (Q9Y7G6)

RNA-dependent RNA polymerase (UniProt Q9Y7G6), EC 2.7.7.48: 9 experimental structures on GenesisL1, 5 ligands bound, 115 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9Y7G6
Protein
RNA-dependent RNA polymerase
EC
2.7.7.48
Experimental structures
9
Predicted models
0
Ligands
5
Pockets
115 · 6 records with a druggable one

Structures

9 records of Q9Y7G6 in the MolNFT archive: 9 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2J7NStructure of the RNAi polymerase from Neurospora crassax-ray diffractionA, BMG20 (best 0.79)
2J7NStructure of the rnai polymerase from neurospora crassax-ray diffractionA, B——
2J7OStructure of the rnai polymerase from neurospora crassax-ray diffractionAMG15 (best 0.66)
2J7OStructure of the rnai polymerase from neurospora crassax-ray diffractionA——
7Y7PQDE-1 in complex with RNA template, RNA primer and AMPNPPx-ray diffractionA, BCA, ZAN20 (best 0.81)
7Y7QQDE-1 in complex with RNA template, RNA primer and 3'-dGTPx-ray diffractionA, BCA, MG, GTP20 (best 0.82)
7Y7RQDE-1 in complex with DNA template, RNA primer and 3'-dGTPx-ray diffractionA, BCA, MG, GTP20 (best 0.80)
7Y7SQDE-1 in complex with DNA template, RNA primer and AMPNPPx-ray diffractionA, BCA, ZAN, MG20 (best 0.83)
7Y7TQDE-1 in complex with 12nt DNA template, ATP and 3'-dGTPx-ray diffractionA, BGTP, MG, ATP—

Ligands

  • MG · Magnesium ion · in 6 records
  • CA · Calcium ion · in 4 records
  • GTP · Guanosine-5'-triphosphate · in 3 records
  • ZAN · 5'-O-[(S)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]amino}phosphoryl]adenosine · in 2 records
  • ATP · Adenosine-5'-triphosphate · in 1 record

Elsewhere

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