UniProt Q9UHB9
Signal recognition particle subunit SRP68 (Q9UHB9)
Signal recognition particle subunit SRP68 (UniProt Q9UHB9): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9UHB9
- Protein
- Signal recognition particle subunit SRP68
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 28 · 4 records with a druggable one
Structures
14 records of Q9UHB9 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4P3E | Structure of the human SRP S domain | x-ray diffraction | C | — | — |
| 4P3E | Structure of the human srp S domain | x-ray diffraction | C | — | — |
| 4P3F | Structure of the human SRP68-RBD | x-ray diffraction | A, B | — | — |
| 4P3F | Structure of the human SRP68-rbd | x-ray diffraction | A, B | — | — |
| 5M72 | Structure of the human SRP68-72 protein-binding domain complex | x-ray diffraction | B | — | — |
| 5M72 | Structure of the human SRP68-72 protein-binding domain complex | x-ray diffraction | B | — | — |
| 5M73 | Structure of the human SRP S domain with SRP72 RNA-binding domain | x-ray diffraction | C, G | MG | 11 (best 0.73) |
| 5M73 | Structure of the human srp S domain with SRP72 RNA-binding domain | x-ray diffraction | C, G | MG | — |
| 5WRV | Complex structure of human SRP72/SRP68 | x-ray diffraction | A | NA | 1 (best 0.42) |
| 5WRV | Complex structure of human SRP72/SRP68 | x-ray diffraction | A | NA | — |
| 7NFX | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | electron microscopy | u | — | — |
| 8QVW | Cryo-EM structure of the peptide binding domain of human SRP68/72 | electron microscopy | A | — | 4 (best 0.56) |
| 8QVX | Structure of the PBD of human SRP68/72 (cryoSPARC 3DFlex) | electron microscopy | A | — | 4 (best 0.63) |
| Q9UHB9 | AlphaFold monomer V2.0 prediction for signal recognition particle subunit SRP68 (Q9UHB9) | predicted | A | — | 8 (best 0.64) |
Ligands
Experiment against prediction
- 4P3E chain C against the predicted model Q9UHB9: TM-score 0.99, RMSD 0.64 Å
- 4P3E chain C against the predicted model Q9UHB9: TM-score 0.99, RMSD 0.64 Å
- 5M73 chain C against the predicted model Q9UHB9: TM-score 0.98, RMSD 0.96 Å
- 5M73 chain C against the predicted model Q9UHB9: TM-score 0.98, RMSD 0.96 Å
- 5M73 chain G against the predicted model Q9UHB9: TM-score 0.98, RMSD 0.76 Å
- 5M73 chain G against the predicted model Q9UHB9: TM-score 0.98, RMSD 0.76 Å
- 7NFX chain u against the predicted model Q9UHB9: TM-score 0.98, RMSD 0.79 Å
- 4P3F chain B against the predicted model Q9UHB9: TM-score 0.91, RMSD 1.43 Å
- 4P3F chain B against the predicted model Q9UHB9: TM-score 0.91, RMSD 1.43 Å
- 4P3F chain A against the predicted model Q9UHB9: TM-score 0.89, RMSD 1.09 Å
Elsewhere
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