MolNFT v1 · #436785 · protein
AlphaFold monomer V2.0 prediction for signal recognition particle subunit SRP68 (Q9UHB9)
Q9UHB9: “AlphaFold monomer V2.0 prediction for signal recognition particle subunit SRP68 (Q9UHB9)”. 8 pockets (best druggability 0.64). MolNFT v1 #436785 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9UHB9
- Type
- protein
- Length
- 627 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Signal recognition particle subunit SRP68
- UniProt
- Q9UHB9
- Pockets
- 8 · best druggability 0.64
Structure
1 distinct chain · 61% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Signal recognition particle subunit SRP68 | protein | 627 | 61% helix, 2% strand | Q9UHB9 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 415 | 0.64 | 0.78 | 38 | empty |
| 2 | 267 | 0.58 | 0.78 | 28 | empty |
| 3 | 212 | 0.54 | 0.78 | 27 | empty |
| 4 | 55 | 0.40 | 0.81 | 13 | empty |
| 5 | 107 | 0.39 | 0.75 | 20 | empty |
Compared structures
- 5M73 · Structure of the human srp S domain with SRP72 RNA-binding domain · an experimental structure of the same protein · chain A against G, TM-score 0.31
- 5M73 · Structure of the human SRP S domain with SRP72 RNA-binding domain · an experimental structure of the same protein · chain A against G, TM-score 0.31
- 7NFX · Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A · an experimental structure of the same protein · chain A against u, TM-score 0.31
- 7QWQ · Ternary complex of ribosome nascent chain with SRP and NAC · an experimental structure of the same protein · chain A against v, TM-score 0.31
- 4P3F · Structure of the human SRP68-rbd · an experimental structure of the same protein · chain A against B, TM-score 0.29
- 4P3F · Structure of the human SRP68-RBD · an experimental structure of the same protein · chain A against B, TM-score 0.29
- 4P3E · Structure of the human SRP S domain · an experimental structure of the same protein · chain A against C, TM-score 0.28
- 4P3E · Structure of the human srp S domain · an experimental structure of the same protein · chain A against C, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UHB9
- Elsewhere: UniProt Q9UHB9 · AlphaFold DB Q9UHB9
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