UniProt Q9P0X4
Voltage-dependent T-type calcium channel subunit alpha-1I (Q9P0X4)
Voltage-dependent T-type calcium channel subunit alpha-1I (UniProt Q9P0X4): 8 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9P0X4
- Protein
- Voltage-dependent T-type calcium channel subunit alpha-1I
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 80 · 4 records with a druggable one
Structures
9 records of Q9P0X4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7WLI | CryoEM structure of human low-voltage activated T-type calcium channel CaV3.3 (apo) | electron microscopy | A | CA, NAG, 3PE, Y01 | 20 (best 0.85) |
| 7WLI | Cryoem structure of human low-voltage activated T-type calcium channel CAV3.3 (apo) | electron microscopy | A | CA, NAG, 3PE, Y01 | — |
| 7WLJ | CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with… | electron microscopy | A | MWV, 3PE, CA, Y01, NAG | 20 (best 0.85) |
| 7WLJ | Cryoem structure of human low-voltage activated T-type calcium channel CAV3.3 in complex with… | electron microscopy | A | MWV, 3PE, CA, Y01, NAG | — |
| 7WLK | CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with… | electron microscopy | A | 7TB, 3PE, CA, Y01, NAG | 20 (best 0.85) |
| 7WLK | Cryoem structure of human low-voltage activated T-type calcium channel CAV3.3 in complex with… | electron microscopy | A | 7TB, 3PE, CA, Y01, NAG | — |
| 7WLL | CryoEM structure of human low-voltage activated T-type calcium channel Cav3.3 in complex with… | electron microscopy | A | 1II, 3PE, CA, Y01, NAG | 20 (best 0.85) |
| 7WLL | Cryoem structure of human low-voltage activated T-type calcium channel CAV3.3 in complex with… | electron microscopy | A | 1II, 3PE, CA, Y01, NAG | — |
| Q9P0X4 | AlphaFold monomer V2.0 prediction for voltage-dependent T-type calcium channel subunit alpha-1I… | predicted | A | — | — |
Ligands
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 8 records
- CA · Calcium ion · in 8 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- Y01 · Cholesterol hemisuccinate · in 8 records
- 1II · 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1~{H}-benzimidazol-2-one · in 2 records
- 7TB · 2-[diethyl(methyl)-$l^{4}-azanyl]ethyl 4-[(2-octoxyphenyl)carbonylamino]benzoate · in 2 records
- MWV · (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](methyl) amino}ethyl)-6-fluoro-1-(propan-2-yl)-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate · in 2 records
Experiment against prediction
- 7WLK chain A against the predicted model Q9P0X4: TM-score 0.98, RMSD 1.76 Å
- 7WLK chain A against the predicted model Q9P0X4: TM-score 0.98, RMSD 1.76 Å
- 7WLJ chain A against the predicted model Q9P0X4: TM-score 0.98, RMSD 1.77 Å
- 7WLJ chain A against the predicted model Q9P0X4: TM-score 0.98, RMSD 1.77 Å
- 7WLL chain A against the predicted model Q9P0X4: TM-score 0.97, RMSD 1.82 Å
- 7WLL chain A against the predicted model Q9P0X4: TM-score 0.97, RMSD 1.82 Å
- 7WLI chain A against the predicted model Q9P0X4: TM-score 0.97, RMSD 1.89 Å
- 7WLI chain A against the predicted model Q9P0X4: TM-score 0.97, RMSD 1.89 Å
Elsewhere
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