UniProt Q9NZV8
Potassium voltage-gated channel subfamily D member 2 (Q9NZV8)
Potassium voltage-gated channel subfamily D member 2 (UniProt Q9NZV8): 30 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 228 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NZV8
- Protein
- Potassium voltage-gated channel subfamily D member 2
- Experimental structures
- 30
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 228 · 14 records with a druggable one
Structures
31 records of Q9NZV8 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7E7Z | CryoEM structure of the human Kv4.2-KChIP1 complex, transmembrane region | electron microscopy | A, B, C, D | — | 17 (best 0.80) |
| 7E7Z | Cryoem structure of the human KV4.2-KCHIP1 complex, transmembrane region | electron microscopy | A, B, C, D | — | — |
| 7E83 | CryoEM structure of the human Kv4.2-KChIP1 complex, intracellular region | electron microscopy | C, A, D, G | — | 16 (best 0.81) |
| 7E83 | Cryoem structure of the human KV4.2-KCHIP1 complex, intracellular region | electron microscopy | C, A, D, G | — | — |
| 7E87 | CryoEM structure of the human Kv4.2-DPP6S complex, transmembrane and intracellular region | electron microscopy | B, A, C, D | — | 20 (best 0.82) |
| 7E87 | Cryoem structure of the human KV4.2-DPP6S complex, transmembrane and intracellular region | electron microscopy | B, A, C, D | — | — |
| 7E8B | CryoEM structure of human Kv4.2-DPP6S complex | electron microscopy | B, A, D, C | — | 4 (best 0.85) |
| 7E8B | Cryoem structure of human KV4.2-DPP6S complex | electron microscopy | B, A, D, C | — | — |
| 7E8E | CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex, transmembrane and intracellular region | electron microscopy | C, D, A, B | — | 18 (best 0.86) |
| 7E8E | Cryoem structure of human KV4.2-DPP6S-KCHIP1 complex, transmembrane and intracellular region | electron microscopy | C, D, A, B | — | — |
| 7E8H | CryoEM structure of human Kv4.2-DPP6S-KChIP1 complex | electron microscopy | B, A, D, C | — | 9 (best 0.87) |
| 7E8H | Cryoem structure of human KV4.2-DPP6S-KCHIP1 complex | electron microscopy | B, A, D, C | — | — |
| 7F0J | CryoEM structure of human Kv4.2 | electron microscopy | B, C, F, H | ZN | 20 (best 0.82) |
| 7F0J | Cryoem structure of human KV4.2 | electron microscopy | B, C, F, H | ZN | — |
| 7F3F | CryoEM structure of human Kv4.2-KChIP1 complex | electron microscopy | A, B, D, G | — | 20 (best 0.82) |
| 7F3F | Cryoem structure of human KV4.2-KCHIP1 complex | electron microscopy | A, B, D, G | — | — |
| 7UK5 | Human Kv4.2-KChIP2 channel complex in an open state, transmembrane region | electron microscopy | A, B, C, D | K | 12 (best 0.82) |
| 7UK5 | Human KV4.2-KCHIP2 channel complex in an open state, transmembrane region | electron microscopy | A, B, C, D | K | — |
| 7UKC | Human Kv4.2-KChIP2 channel complex in an inactivated state, class 1, transmembrane region | electron microscopy | B, C, D, A | K | 18 (best 0.80) |
| 7UKC | Human KV4.2-KCHIP2 channel complex in an inactivated state, class 1, transmembrane region | electron microscopy | B, C, D, A | K | — |
| 7UKD | Human Kv4.2-KChIP2 channel complex in an inactivated state, class 2, transmembrane region | electron microscopy | A, B, C, D | K | 20 (best 0.77) |
| 7UKD | Human KV4.2-KCHIP2 channel complex in an inactivated state, class 2, transmembrane region | electron microscopy | A, B, C, D | K | — |
| 7UKE | Human Kv4.2-KChIP2 channel complex in an intermediate state, transmembrane region | electron microscopy | A, B, C, D | K | 17 (best 0.74) |
| 7UKE | Human KV4.2-KCHIP2 channel complex in an intermediate state, transmembrane region | electron microscopy | A, B, C, D | K | — |
| 7UKF | Human Kv4.2-KChIP2 channel complex in a putative resting state, transmembrane region | electron microscopy | A, B, C, D | K, HG | 20 (best 0.63) |
| 7UKF | Human KV4.2-KCHIP2 channel complex in a putative resting state, transmembrane region | electron microscopy | A, B, C, D | K, HG | — |
| 7UKG | Human Kv4.2-KChIP2-DPP6 channel complex in an open state, transmembrane region | electron microscopy | A, B, C, D | K | 17 (best 0.81) |
| 7UKG | Human KV4.2-KCHIP2-DPP6 channel complex in an open state, transmembrane region | electron microscopy | A, B, C, D | K | — |
| 7UKH | Human Kv4.2-KChIP2-DPP6 channel complex in an open state, intracellular region | electron microscopy | A, B, C, D | ZN | — |
| 7UKH | Human KV4.2-KCHIP2-DPP6 channel complex in an open state, intracellular region | electron microscopy | A, B, C, D | ZN | — |
| Q9NZV8 | AlphaFold monomer V2.0 prediction for potassium voltage-gated channel subfamily D member 2 (Q9NZV8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7UK5 chain C against the predicted model Q9NZV8: TM-score 0.94, RMSD 1.69 Å
- 7UK5 chain B against the predicted model Q9NZV8: TM-score 0.94, RMSD 1.69 Å
- 7UK5 chain A against the predicted model Q9NZV8: TM-score 0.94, RMSD 1.69 Å
- 7UK5 chain A against the predicted model Q9NZV8: TM-score 0.94, RMSD 1.69 Å
- 7UK5 chain D against the predicted model Q9NZV8: TM-score 0.94, RMSD 1.69 Å
- 7UKG chain D against the predicted model Q9NZV8: TM-score 0.93, RMSD 1.79 Å
- 7UKG chain C against the predicted model Q9NZV8: TM-score 0.93, RMSD 1.79 Å
- 7UKG chain A against the predicted model Q9NZV8: TM-score 0.93, RMSD 1.79 Å
- 7UKG chain A against the predicted model Q9NZV8: TM-score 0.93, RMSD 1.79 Å
- 7UKG chain B against the predicted model Q9NZV8: TM-score 0.93, RMSD 1.79 Å
Elsewhere
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