UniProt Q9NW15
Anoctamin-10 (Q9NW15)
Anoctamin-10 (UniProt Q9NW15): 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 96 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9NW15
- Protein
- Anoctamin-10
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 96 · 5 records with a druggable one
Structures
11 records of Q9NW15 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5OC9 | Crystal Structure of human TMEM16K / Anoctamin 10 | x-ray diffraction | A, B | CA, 79M | 20 (best 0.81) |
| 5OC9 | Crystal structure of human TMEM16K / anoctamin 10 | x-ray diffraction | A, B | CA, 79M | — |
| 6R65 | Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2) | x-ray diffraction | A, B | CA | 20 (best 0.79) |
| 6R65 | Crystal structure of human TMEM16K / anoctamin 10 (form 2) | x-ray diffraction | A, B | CA | — |
| 6R7X | CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form) | electron microscopy | A, B | CA, PC1, UMQ | 20 (best 0.77) |
| 6R7X | Cryoem structure of calcium-bound human TMEM16K / anoctamin 10 in detergent (2MM CA2+, closed form) | electron microscopy | A, B | CA, PC1, UMQ | — |
| 6R7Y | CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (low Ca2+, closed form) | electron microscopy | A, B | CA | 20 (best 0.78) |
| 6R7Y | Cryoem structure of calcium-bound human TMEM16K / anoctamin 10 in detergent (low CA2+, closed form) | electron microscopy | A, B | CA | — |
| 6R7Z | CryoEM structure of calcium-free human TMEM16K / Anoctamin 10 in detergent (closed form) | electron microscopy | A, B | — | 16 (best 0.78) |
| 6R7Z | Cryoem structure of calcium-free human TMEM16K / anoctamin 10 in detergent (closed form) | electron microscopy | A, B | — | — |
| Q9NW15 | AlphaFold monomer V2.0 prediction for anoctamin-10 (Q9NW15) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6R65 chain A against the predicted model Q9NW15: TM-score 0.98, RMSD 1.40 Å
- 6R65 chain A against the predicted model Q9NW15: TM-score 0.98, RMSD 1.40 Å
- 6R65 chain B against the predicted model Q9NW15: TM-score 0.98, RMSD 1.46 Å
- 6R65 chain B against the predicted model Q9NW15: TM-score 0.98, RMSD 1.46 Å
- 5OC9 chain A against the predicted model Q9NW15: TM-score 0.97, RMSD 1.43 Å
- 5OC9 chain A against the predicted model Q9NW15: TM-score 0.97, RMSD 1.43 Å
- 5OC9 chain B against the predicted model Q9NW15: TM-score 0.97, RMSD 1.44 Å
- 5OC9 chain B against the predicted model Q9NW15: TM-score 0.97, RMSD 1.44 Å
- 6R7Y chain A against the predicted model Q9NW15: TM-score 0.94, RMSD 2.48 Å
- 6R7Y chain A against the predicted model Q9NW15: TM-score 0.94, RMSD 2.48 Å
Elsewhere
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