UniProt Q9CR68
Cytochrome b-c1 complex subunit Rieske, mitochondrial (Q9CR68)
Cytochrome b-c1 complex subunit Rieske, mitochondrial (UniProt Q9CR68), EC 7.1.1.8: 21 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 91 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9CR68
- Protein
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- EC
- 7.1.1.8
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 91 · 14 records with a druggable one
Structures
22 records of Q9CR68 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7O37 | Murine supercomplex CIII2CIV in the assembled locked conformation | electron microscopy | E, P, T | 3PE, HEC, FES, PC1 | 8 (best 0.86) |
| 7O37 | Murine supercomplex CIII2CIV in the assembled locked conformation | electron microscopy | E, P, T | 3PE, FES, PC1 | — |
| 7O3C | Murine supercomplex CIII2CIV in the mature unlocked conformation | electron microscopy | E, P, T | 3PE, FES, PC1, HEC, CDL | — |
| 7O3C | Murine supercomplex CIII2CIV in the mature unlocked conformation | electron microscopy | E, P, T | 3PE, FES, PC1, HEC, CDL | — |
| 7O3E | Murine supercomplex CIII2CIV in the intermediate locked conformation | electron microscopy | P, T | — | 5 (best 0.85) |
| 7O3E | Murine supercomplex CIII2CIV in the intermediate locked conformation | electron microscopy | P, T | — | — |
| 7O3H | Murine CIII2 focus-refined from supercomplex CICIII2 | electron microscopy | E, P, T | 3PE, FES, PC1, HEC | 11 (best 0.84) |
| 7O3H | Murine CIII2 focus-refined from supercomplex CICIII2 | electron microscopy | E, P, T | 3PE, FES, PC1, HEC | — |
| 8IAO | Respiratory complex CI:CIII2, type I, Wild type mouse under thermoneutral temperature | electron microscopy | AE, AI, Ae, Ai | PC1 | 1 (best 0.82) |
| 8IAR | Respiratory complex CIII2, focus-refined of type I, Wild type mouse under thermoneutral temperature | electron microscopy | AE, AI, Ae, Ai | PC1 | 11 (best 0.80) |
| 8IB4 | Respiratory complex CI:CIII2, type IA, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae | 3PH | — |
| 8IB7 | Respiratory complex CIII2, focus-refined of type IA, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae | 3PH | 12 (best 0.80) |
| 8IB9 | Respiratory complex CI:CIII2, type IB, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae | — | 1 (best 0.80) |
| 8IBC | Respiratory complex CIII2, focus-refined of type IB, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae | — | 12 (best 0.80) |
| 8IBD | Respiratory complex CI:CIII2, type II, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae, Ai | 3PE, 3PH | 2 (best 0.84) |
| 8IBG | Respiratory complex CIII2, focus-refined of type II, Wild type mouse under cold temperature | electron microscopy | AE, AI, Ae, Ai | 3PE, 3PH | 12 (best 0.85) |
| 8IC2 | Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature | electron microscopy | AE, AI, Ae | — | 2 (best 0.83) |
| 8IC5 | Respiratory complex CIII2, focus-refined of type I, PERK -/- mouse under cold temperature | electron microscopy | AE, AI, Ae | — | 11 (best 0.80) |
| 8PW5 | CS respirasome from murine liver | electron microscopy | E, P, T | 3PE, FES, PC1 | 1 (best 0.88) |
| 8PW6 | C respirasome from murine liver | electron microscopy | E, P, T | 3PE, FES, PC1 | — |
| 8PW7 | A respirasome from murine liver | electron microscopy | E, P, T | 3PE, FES, PC1 | 2 (best 0.81) |
| Q9CR68 | AlphaFold monomer V2.0 prediction for cytochrome B-C1 complex subunit rieske, mitochondrial (Q9CR68) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8PW5 chain P against the predicted model Q9CR68: TM-score 0.96, RMSD 1.04 Å
- 8PW7 chain P against the predicted model Q9CR68: TM-score 0.95, RMSD 1.17 Å
- 8PW7 chain E against the predicted model Q9CR68: TM-score 0.95, RMSD 1.26 Å
- 8PW6 chain E against the predicted model Q9CR68: TM-score 0.95, RMSD 1.30 Å
- 8PW5 chain E against the predicted model Q9CR68: TM-score 0.94, RMSD 1.34 Å
- 8IAO chain AE against the predicted model Q9CR68: TM-score 0.87, RMSD 2.04 Å
- 8IAR chain AE against the predicted model Q9CR68: TM-score 0.87, RMSD 2.04 Å
- 8IB9 chain AE against the predicted model Q9CR68: TM-score 0.87, RMSD 2.07 Å
- 8IBC chain AE against the predicted model Q9CR68: TM-score 0.87, RMSD 2.07 Å
- 8IB4 chain AE against the predicted model Q9CR68: TM-score 0.86, RMSD 2.10 Å
Elsewhere
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