UniProt Q980A5
Translation initiation factor 2 subunit gamma (Q980A5)
Translation initiation factor 2 subunit gamma (UniProt Q980A5), EC 3.6.5.3: 61 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q980A5
- Protein
- Translation initiation factor 2 subunit gamma
- EC
- 3.6.5.3
- Experimental structures
- 61
- Predicted models
- 1
- Ligands
- 6
Structures
62 records of Q980A5 in the MolNFT archive: 61 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AHO | Structure of the archaeal initiation factor eIF2 alpha-gamma heterodimer from Sulfolobus… | x-ray diffraction | A | — | — |
| 2AHO | Structure of the archaeal initiation factor EIF2 alpha-gamma heterodimer from sulfolobus… | x-ray diffraction | A | — | — |
| 2PLF | The structure of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the nucleotide-free… | x-ray diffraction | A | — | — |
| 2PLF | The structure of AIF2GAMMA subunit from the archaeon sulfolobus solfataricus in the nucleotide-free… | x-ray diffraction | A | — | — |
| 2PMD | The structures of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the GDP-bound form. | x-ray diffraction | A, B | — | — |
| 2PMD | The structures of AIF2GAMMA subunit from the archaeon sulfolobus solfataricus in the GDP-bound form. | x-ray diffraction | A, B | — | — |
| 2QMU | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | A | — | — |
| 2QMU | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | A | — | — |
| 2QN6 | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | A | — | — |
| 2QN6 | Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the… | x-ray diffraction | A | — | — |
| 3CW2 | Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus… | x-ray diffraction | A, B, E, F | — | — |
| 3CW2 | Crystal structure of the intact archaeal translation initiation factor 2 from sulfolobus… | x-ray diffraction | A, B, E, F | — | — |
| 3I1F | Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p | x-ray diffraction | A, B | — | — |
| 3I1F | Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with GPP(CH2)P | x-ray diffraction | A, B | — | — |
| 3PEN | Structure of archaeal initiation factor aIF2gamma subunit delta 37-47 from Sulfolobus solfataricus… | x-ray diffraction | A | — | — |
| 3PEN | Structure of archaeal initiation factor AIF2GAMMA subunit delta 37-47 from sulfolobus solfataricus… | x-ray diffraction | A | — | — |
| 3QSY | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea | x-ray diffraction | A | — | — |
| 3QSY | Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in archaea | x-ray diffraction | A | — | — |
| 3SJZ | The structure of aIF2gamma subunit delta 41-45 from archaeon Sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 3SJZ | The structure of AIF2GAMMA subunit delta 41-45 from archaeon sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 3V11 | Structure of the ternary initiation complex AIF2:GDPNP:methionylated initiator TRNA | x-ray diffraction | A | — | — |
| 3V11 | Structure of the ternary initiation complex AIF2:GDPNP:METHIONYLATED initiator tRNA | x-ray diffraction | A | — | — |
| 4M0L | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus complexed with GDP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4M0L | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus complexed with GDP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4M2L | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in… | x-ray diffraction | A | — | — |
| 4M2L | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus in… | x-ray diffraction | A | — | — |
| 4M4S | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with… | x-ray diffraction | A | — | — |
| 4M4S | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus in complex with… | x-ray diffraction | A | — | — |
| 4M53 | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with… | x-ray diffraction | A | — | — |
| 4M53 | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus in complex with… | x-ray diffraction | A | — | — |
| 4NBS | The structure of aIF2gamma subunit H20F from archaeon Sulfolobus solfataricus complexed with GDPCP | x-ray diffraction | A | — | — |
| 4NBS | The structure of AIF2GAMMA subunit H20F from archaeon sulfolobus solfataricus complexed with gdpcp | x-ray diffraction | A | — | — |
| 4QFM | The structure of aIF2gamma subunit D152A from archaeon Sulfolobus solfataricus complexed with GDPCP | x-ray diffraction | A | — | — |
| 4QFM | The structure of AIF2GAMMA subunit D152A from archaeon sulfolobus solfataricus complexed with gdpcp | x-ray diffraction | A | — | — |
| 4QHY | The structure of aIF2gamma subunit H20F/D152A from archaeon Sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 4QHY | The structure of AIF2GAMMA subunit H20F/D152A from archaeon sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 4RCY | Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GTP | x-ray diffraction | A | — | — |
| 4RCY | Structure of AIF2-gamma D19A variant from sulfolobus solfataricus bound to GTP | x-ray diffraction | A | — | — |
| 4RCZ | Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDPNP | x-ray diffraction | A | — | — |
| 4RCZ | Structure of AIF2-gamma D19A variant from sulfolobus solfataricus bound to gdpnp | x-ray diffraction | A | — | — |
| 4RD0 | Structure of aIF2-gamma D19A variant from Sulfolobus solfataricus bound to GDP | x-ray diffraction | A | — | — |
| 4RD0 | Structure of AIF2-gamma D19A variant from sulfolobus solfataricus bound to GDP | x-ray diffraction | A | — | — |
| 4RD1 | Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GTP | x-ray diffraction | A | — | — |
| 4RD1 | Structure of AIF2-gamma H97A variant from sulfolobus solfataricus bound to GTP | x-ray diffraction | A | — | — |
| 4RD2 | Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDPNP | x-ray diffraction | A | — | — |
| 4RD2 | Structure of AIF2-gamma H97A variant from sulfolobus solfataricus bound to gdpnp | x-ray diffraction | A | — | — |
| 4RD3 | Structure of aIF2-gamma H97A variant from Sulfolobus solfataricus bound to GDP and Pi | x-ray diffraction | A | — | — |
| 4RD3 | Structure of AIF2-gamma H97A variant from sulfolobus solfataricus bound to GDP and pi | x-ray diffraction | A | — | — |
| 4RD4 | Structure of aIF2 gamma from sulfolobus solfataricus bound to gdpnp | x-ray diffraction | A | — | — |
| 4RD4 | Structure of AIF2 gamma from sulfolobus solfataricus bound to gdpnp | x-ray diffraction | A | — | — |
| 4RD6 | Structure of aIF2-gamma from Sulfolobus solfataricus bound to GDP | x-ray diffraction | A | — | — |
| 4RD6 | Structure of AIF2-gamma from sulfolobus solfataricus bound to GDP | x-ray diffraction | A | — | — |
| 4RJL | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 4RJL | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus complexed with… | x-ray diffraction | A | — | — |
| 5DSZ | Gamma-subunit of the translation initiation factor 2 from S. solfataricus | x-ray diffraction | A, B | — | — |
| 5DSZ | Gamma-subunit of the translation initiation factor 2 from S. solfataricus | x-ray diffraction | A, B | — | — |
| 6H6K | The structure of the fkr mutant of the archaeal translation initiation factor 2 gamma subunit in… | x-ray diffraction | A, B, C, D, E | GCP, NA | — |
| 6I5M | Gamma subunit of the translation initiation factor 2 from Sulfolobus solfataricus in complex with… | x-ray diffraction | A | GDP, MG, NA | — |
| 6I5M | Gamma subunit of the translation initiation factor 2 from sulfolobus solfataricus in complex with… | x-ray diffraction | A | GDP, MG, NA | — |
| 6SW9 | IC2A model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid… | electron microscopy | 7 | MET, GNP, MG | — |
2 records more on the page itself.
Ligands
Experiment against prediction
- 4QFM chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.79 Å
- 4QFM chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.79 Å
- 6H6K chain E against the predicted model Q980A5: TM-score 0.99, RMSD 0.80 Å
- 4QHY chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.82 Å
- 4QHY chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.82 Å
- 3PEN chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.81 Å
- 3PEN chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.81 Å
- 4M53 chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.85 Å
- 4M53 chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.85 Å
- 4NBS chain A against the predicted model Q980A5: TM-score 0.99, RMSD 0.89 Å
Elsewhere
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