UniProt Q96PD4
Interleukin-17F (Q96PD4)
Interleukin-17F (UniProt Q96PD4): 13 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96PD4
- Protein
- Interleukin-17F
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 44 · 5 records with a druggable one
Structures
14 records of Q96PD4 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JVF | Crystal structure of an Interleukin-17 receptor complex | x-ray diffraction | A, B | — | — |
| 3JVF | Crystal structure of an interleukin-17 receptor complex | x-ray diffraction | A, B | — | — |
| 5N92 | Crystal structure of human il-17AF | x-ray diffraction | F | NAG, FUC | — |
| 5NAN | Crystal Structure of human IL-17AF in complex with human IL-17RA | x-ray diffraction | E, F | NAG, GAL | 18 (best 0.72) |
| 5NAN | Crystal structure of human il-17AF in complex with human il-17RA | x-ray diffraction | E, F | NAG, GAL | — |
| 6HG4 | Crystal Structure of the human IL-17RC ECD in complex with human IL-17F | x-ray diffraction | A | — | 2 (best 0.72) |
| 6HG4 | Crystal structure of the human il-17RC ecd in complex with human il- 17F | x-ray diffraction | A | — | — |
| 6HG9 | Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II | x-ray diffraction | A | — | 2 (best 0.72) |
| 6HG9 | Crystal structure of the human il-17RC ecd in complex with human il- 17F, crystal form II | x-ray diffraction | A | — | — |
| 6HGO | Crystal Structure of human IL-17F | x-ray diffraction | A, B, C, D | NAG, SO4 | 14 (best 0.85) |
| 6HGO | Crystal structure of human il-17F | x-ray diffraction | A, B, C, D | NAG, SO4 | — |
| 6PPG | Crystal structure of IL17FF bound to Fab fragments of MCAF5352A | x-ray diffraction | F, G | NAG, CD | — |
| 8RUU | Fabs derived from bimekizumab in complex with IL-17F | x-ray diffraction | X, Y | NAG, FUL | 8 (best 0.78) |
| Q96PD4 | AlphaFold monomer V2.0 prediction for interleukin-17F (Q96PD4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6HGO chain B against the predicted model Q96PD4: TM-score 0.98, RMSD 1.02 Å
- 6HGO chain B against the predicted model Q96PD4: TM-score 0.98, RMSD 1.02 Å
- 6HGO chain D against the predicted model Q96PD4: TM-score 0.97, RMSD 0.84 Å
- 6HGO chain D against the predicted model Q96PD4: TM-score 0.97, RMSD 0.84 Å
- 6HGO chain C against the predicted model Q96PD4: TM-score 0.96, RMSD 0.93 Å
- 6HGO chain C against the predicted model Q96PD4: TM-score 0.96, RMSD 0.93 Å
- 6PPG chain G against the predicted model Q96PD4: TM-score 0.95, RMSD 1.05 Å
- 6HGO chain A against the predicted model Q96PD4: TM-score 0.95, RMSD 0.94 Å
- 6HGO chain A against the predicted model Q96PD4: TM-score 0.95, RMSD 0.94 Å
- 6PPG chain F against the predicted model Q96PD4: TM-score 0.94, RMSD 1.23 Å
Elsewhere
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