UniProt Q8VGC3
Voltage-dependent L-type calcium channel subunit beta-2 (Q8VGC3)
Voltage-dependent L-type calcium channel subunit beta-2 (UniProt Q8VGC3): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8VGC3
- Protein
- Voltage-dependent L-type calcium channel subunit beta-2
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 0 records with a druggable one
Structures
11 records of Q8VGC3 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T0H | Crystal structure of the Rattus norvegicus voltage gated calcium channel beta subunit isoform 2a | x-ray diffraction | A, B | — | — |
| 1T0H | Crystal structure of the rattus norvegicus voltage gated calcium channel beta subunit isoform 2A | x-ray diffraction | A, B | — | — |
| 1T0J | Crystal structure of a complex between voltage-gated calcium channel beta2a subunit and a peptide… | x-ray diffraction | A, B | — | — |
| 1T0J | Crystal structure of a complex between voltage-gated calcium channel BETA2A subunit and a peptide… | x-ray diffraction | A, B | — | — |
| 3JBR | Cryo-EM structure of the rabbit voltage-gated calcium channel Cav1.1 complex at 4.2 angstrom | electron microscopy | B | — | — |
| 3JBR | Cryo-EM structure of the rabbit voltage-gated calcium channel CAV1.1 complex at 4.2 ångström | electron microscopy | B | — | — |
| 5V2P | CaV beta2a subunit: CaV1.2 AID-CAP complex | x-ray diffraction | A | NI | 3 (best 0.33) |
| 5V2P | Cav BETA2A subunit: CAV1.2 aid-cap complex | x-ray diffraction | A | NI | — |
| 5V2Q | CaV beta2a subunit: CaV1.2 AID-CEN complex | x-ray diffraction | A | CL | 1 (best 0.46) |
| 5V2Q | Cav BETA2A subunit: CAV1.2 aid-cen complex | x-ray diffraction | A | CL | — |
| Q8VGC3 | AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit beta-2… | predicted | A | — | — |
Ligands
Experiment against prediction
- 1T0H chain A against the predicted model Q8VGC3: TM-score 0.99, RMSD 0.40 Å
- 1T0H chain A against the predicted model Q8VGC3: TM-score 0.99, RMSD 0.40 Å
- 1T0J chain A against the predicted model Q8VGC3: TM-score 0.99, RMSD 0.41 Å
- 1T0J chain A against the predicted model Q8VGC3: TM-score 0.99, RMSD 0.41 Å
- 5V2Q chain A against the predicted model Q8VGC3: TM-score 0.98, RMSD 0.96 Å
- 5V2Q chain A against the predicted model Q8VGC3: TM-score 0.98, RMSD 0.96 Å
- 5V2P chain A against the predicted model Q8VGC3: TM-score 0.97, RMSD 1.44 Å
- 5V2P chain A against the predicted model Q8VGC3: TM-score 0.97, RMSD 1.44 Å
- 3JBR chain B against the predicted model Q8VGC3: TM-score 0.97, RMSD 1.37 Å
- 3JBR chain B against the predicted model Q8VGC3: TM-score 0.97, RMSD 1.37 Å
Elsewhere
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