UniProt Q8IZF0
Sodium leak channel non-selective protein (Q8IZF0)
Sodium leak channel non-selective protein (UniProt Q8IZF0): 10 experimental structures on GenesisL1, 5 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8IZF0
- Protein
- Sodium leak channel non-selective protein
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 46 · 3 records with a druggable one
Structures
10 records of Q8IZF0 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6XIW | Cryo-EM structure of the sodium leak channel NALCN-FAM155A complex | electron microscopy | A | NAG, PEV, PGV, Y01 | 20 (best 0.88) |
| 6XIW | Cryo-EM structure of the sodium leak channel nalcn-FAM155A complex | electron microscopy | A | NAG, PEV, PGV, Y01 | — |
| 7CM3 | Cryo-EM structure of human NALCN in complex with FAM155A | electron microscopy | A | NAG, PC1 | 17 (best 0.87) |
| 7CM3 | Cryo-EM structure of human nalcn in complex with FAM155A | — | — | — | |
| 7SX3 | Human nalcn-FAM155A-UNC79-UNC80 channelosome with cam bound, conformation 1/2 | electron microscopy | A | NAG, PEV, PGV, Y01 | — |
| 7SX4 | Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 2/2 | electron microscopy | A | NAG, PEV, PGV, Y01 | 9 (best 0.87) |
| 7SX4 | Human nalcn-FAM155A-UNC79-UNC80 channelosome with cam bound, conformation 2/2 | electron microscopy | A | NAG, PEV, PGV, Y01 | — |
| 7WJI | Architecture of the human NALCN channelosome | electron microscopy | C | — | — |
| 7WJI | Architecture of the human nalcn channelosome | electron microscopy | C | — | — |
| Q8IZF0 | AlphaFold monomer V2.0 prediction for sodium leak channel non- selective protein (Q8IZF0) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
- PEV · (1S)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 5 records
- PGV · (1R)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11E)-octadec-11-enoate · in 5 records
- Y01 · Cholesterol hemisuccinate · in 5 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 1 record
Elsewhere
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