UniProt Q86U86
Protein polybromo-1 (Q86U86)
Protein polybromo-1 (UniProt Q86U86): 56 experimental structures on GenesisL1, 18 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q86U86
- Protein
- Protein polybromo-1
- Experimental structures
- 56
- Predicted models
- 0
- Ligands
- 18
- Pockets
- 34 · 8 records with a druggable one
Structures
56 records of Q86U86 in the MolNFT archive: 56 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KTB | Solution Structure of the Second Bromodomain of Human Polybromo in complex with an acetylated… | solution nmr | B | — | — |
| 2KTB | Solution structure of the second bromodomain of human polybromo in complex with an acetylated… | solution nmr | B | — | — |
| 3G0J | Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 3G0J | Crystal structure of the fifth bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 3HMF | Crystal Structure of the second Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3HMF | Crystal structure of the second bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3IU5 | Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3IU5 | Crystal structure of the first bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3IU6 | Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3IU6 | Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A | — | — |
| 3K2J | Crystal Structure of the 3rd Bromodomain of Human Poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 3K2J | Crystal structure of the 3RD bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 3LJW | Crystal Structure of the Second Bromodomain of Human Polybromo | x-ray diffraction | A, B | — | — |
| 3LJW | Crystal structure of the second bromodomain of human polybromo | x-ray diffraction | A, B | — | — |
| 3MB4 | Crystal Structure of the fifth Bromodomain of Human Poly-bromodomain containing protein 1 (PB1)… | x-ray diffraction | A, B | — | — |
| 3MB4 | Crystal structure of the fifth bromodomain of human poly-bromodomain containing protein 1 (PB1)… | x-ray diffraction | A, B | — | — |
| 3TLP | Crystal structure of the fourth bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 3TLP | Crystal structure of the fourth bromodomain of human poly-bromodomain containing protein 1 (PB1) | x-ray diffraction | A, B | — | — |
| 4Q0N | Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4Q0N | Crystal structure of the fifth bromodomain of human poly-bromodomain containing protein 1 (PB1) in… | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4Q0O | Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in… | x-ray diffraction | A | — | — |
| 4Q0O | Crystal structure of the fifth bromodomain of human poly-bromodomain containing protein 1 (PB1) in… | x-ray diffraction | A | — | — |
| 4Y03 | Crystal Structure of the fifth bromodomain of human PB1 in complex with salicylic acid | x-ray diffraction | A, B | — | — |
| 4Y03 | Crystal structure of the fifth bromodomain of human PB1 in complex with salicylic acid | x-ray diffraction | A, B | — | — |
| 5E7D | Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand | x-ray diffraction | A, B, C, D | 5KL | 7 (best 0.77) |
| 5E7D | Crystal structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand | x-ray diffraction | A, B, C, D | — | — |
| 5FH6 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 10 | x-ray diffraction | A, B, C, D | 5XM | — |
| 5FH6 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 10 | x-ray diffraction | A, B, C, D | — | — |
| 5FH7 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 18 | x-ray diffraction | A, B | 5XL | — |
| 5FH7 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 18 | x-ray diffraction | A, B | — | — |
| 5FH8 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 28 | x-ray diffraction | A, B, C, D | 5XK | — |
| 5FH8 | Crystal structure of the fifth bromodomain of human PB1 in complex with compound 28 | x-ray diffraction | A, B, C, D | — | — |
| 5HRV | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A | 64C | 1 (best 0.57) |
| 5HRV | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A | — | — |
| 5HRW | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A, B | 64E, SO4 | — |
| 5HRW | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A, B | — | — |
| 5HRX | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A, B | 64F | 1 (best 0.78) |
| 5HRX | Crystal structure of the fifth bromodomain of human PB1 in complex with… | x-ray diffraction | A, B | — | — |
| 5II1 | Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | 6BL | 1 (best 0.77) |
| 5II1 | Crystal structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | — | — |
| 5II2 | Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | K, LU2 | — |
| 5II2 | Crystal structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | — | — |
| 5IID | Crystal Structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | 6BK | — |
| 5IID | Crystal structure of the fifth bromodomain of human polybromo (PB1) in complex with… | x-ray diffraction | A, B | — | — |
| 6OXB | First bromo-adjacent homology (BAH) domain of human Polybromo-1 (PBRM1) | x-ray diffraction | B, A, C, D, E, F | SO4, CL | 15 (best 0.79) |
| 6OXB | First bromo-adjacent homology (bah) domain of human polybromo-1 (PBRM1) | x-ray diffraction | B, A, C, D, E, F | SO4, CL | — |
| 6ZN6 | Protein polybromo-1 (PB1 BD2) Bound To MW278 | x-ray diffraction | A, B | QMT | 3 (best 0.51) |
| 6ZN6 | Protein polybromo-1 (PB1 BD2) bound to MW278 | x-ray diffraction | A, B | QMT | — |
| 6ZNV | Protein polybromo-1 (PB1 BD2) bound to DP28 | x-ray diffraction | A | QMW, ZN, CL | — |
| 6ZS3 | Crystal structure of the fifth bromodomain of human protein polybromo-1 in complex with… | x-ray diffraction | A, B | FX5 | 1 (best 0.77) |
| 6ZS3 | Crystal structure of the fifth bromodomain of human protein polybromo- 1 in complex with… | x-ray diffraction | A, B | FX5 | — |
| 6ZS4 | Crystal structure of the fifth bromodomain of human protein polybromo-1 in complex with tert-butyl… | x-ray diffraction | A | QP8 | 1 (best 0.49) |
| 6ZS4 | Crystal structure of the fifth bromodomain of human protein polybromo- 1 in complex with tert-butyl… | x-ray diffraction | A | QP8 | — |
| 7VDV | The overall structure of human chromatin remodeling PBAF-nucleosome complex | electron microscopy | a | — | 4 (best 0.86) |
| 7VDV | The overall structure of human chromatin remodeling pbaf-nucleosome complex | electron microscopy | a | — | — |
| Q86U86 | AlphaFold monomer V2.0 prediction for protein polybromo-1 (Q86U86) | — | — | — |
Ligands
- CL · Chloride ion · in 3 records
- SO4 · Sulfate ion · in 3 records
- FX5 · 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl) phenol · in 2 records
- QMT · 2-[6-azanyl-5-[(3~{R})-3-phenoxypiperidin-1-yl]pyridazin-3-yl]phenol · in 2 records
- QP8 · tert-butyl 4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazine-1-carboxylate · in 2 records
- 5KL · (2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one · in 1 record
- 5XK · 6-chloranyl-3-(2-ethylbutyl)-4~{H}-pyrrolo[1,2-a]quinazolin-5-one · in 1 record
- 5XL · 6-chloranyl-3-[(dimethylamino)methyl]-4~{H}-pyrrolo[1,2-a]quinazolin-5-one · in 1 record
- 5XM · (3~{R})-3-(piperidin-1-ylmethyl)-2,3-dihydro-1~{H}-pyrrolo[1,2-a]quinazolin-5-one · in 1 record
- 64C · 1-ethylisochromeno[3,4-c]pyrazol-5(3H)-one · in 1 record
- 64E · 1-propylisochromeno[3,4-c]pyrazol-5(3H)-one · in 1 record
- 64F · 1-butylisochromeno[3,4-c]pyrazol-5(3H)-one · in 1 record
- 6BK · 2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-1-benzopyran-4-one · in 1 record
- 6BL · 1-methyl[2]benzopyrano[3,4-c]pyrazol-5(3H)-one · in 1 record
- K · Potassium ion · in 1 record
- LU2 · 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one · in 1 record
- QMW · 1-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperidin-4-ol · in 1 record
- ZN · Zinc ion · in 1 record
Elsewhere
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