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Ligand · QP8

QP8 · tert-butyl 4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazine-1-carboxylate

QP8, tert-butyl 4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazine-1-carboxylate (C19 H25 N5 O3, 371.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
QP8
Formula
C19 H25 N5 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

QP8 in 2 structures; the first of them:

  • 6ZS4 · Crystal structure of the fifth bromodomain of human protein polybromo-1 in complex with… · QP8 A801 · binds ILE683, PHE684, ARG686, LEU687, PRO688, GLU692, LEU693, TYR696 and 8 more
  • 6ZS4 · Crystal structure of the fifth bromodomain of human protein polybromo- 1 in complex with… · QP8 A801 · binds ILE683, PHE684, LEU687, PRO688, LEU693, TYR696, MET704, ASP705 and 5 more

Residues it binds most

ILE 2, LEU 2, MET 2, TYR 2, ASN 2, ALA 2, ASP 2, PHE 2, PRO 2, ARG 1 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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