UniProt Q6WNK7
Transcription and mRNA export factor SUS1 (Q6WNK7)
Transcription and mRNA export factor SUS1 (UniProt Q6WNK7): 31 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6WNK7
- Protein
- Transcription and mRNA export factor SUS1
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
32 records of Q6WNK7 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FWB | Sac3:Sus1:Cdc31 complex | x-ray diffraction | C | — | — |
| 3FWB | SAC3:SUS1:CDC31 complex | x-ray diffraction | C | — | — |
| 3FWC | Sac3:Sus1:Cdc31 complex | x-ray diffraction | C, D, G, H, K, L, O, P | — | — |
| 3FWC | SAC3:SUS1:CDC31 complex | x-ray diffraction | C, D, G, H, K, L, O, P | — | — |
| 3KIK | Sgf11:Sus1 complex | x-ray diffraction | A, B, C, D | — | — |
| 3KIK | SGF11:SUS1 complex | x-ray diffraction | A, B, C, D | — | — |
| 3KJL | Sgf11:Sus1 complex | x-ray diffraction | A, B, C, D | — | — |
| 3KJL | SGF11:SUS1 complex | x-ray diffraction | A, B, C, D | — | — |
| 3M99 | Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module | x-ray diffraction | C | — | — |
| 3M99 | Structure of the UBP8-SGF11-SGF73-SUS1 saga dub module | x-ray diffraction | C | — | — |
| 3MHH | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module | x-ray diffraction | B | — | — |
| 3MHH | Structure of the saga UBP8/SGF11/SUS1/SGF73 dub module | x-ray diffraction | B | — | — |
| 3MHS | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde | x-ray diffraction | B | — | — |
| 3MHS | Structure of the saga UBP8/SGF11/SUS1/SGF73 dub module bound to ubiquitin aldehyde | x-ray diffraction | B | — | — |
| 4C31 | Nup1:Sac3:Sus1 complex | x-ray diffraction | B, E | — | — |
| 4C31 | NUP1:SAC3:SUS1 complex | x-ray diffraction | B, E | — | — |
| 4FIP | Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | x-ray diffraction | B, F | — | — |
| 4FIP | Structure of the saga UBP8(S144N)/SGF11(1-72, delta-ZNF)/SUS1/SGF73 dub module | x-ray diffraction | B, F | — | — |
| 4FJC | Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | x-ray diffraction | B, F | — | — |
| 4FJC | Structure of the saga UBP8/SGF11(1-72, delta-ZNF)/SUS1/SGF73 dub module | x-ray diffraction | B, F | — | — |
| 4FK5 | Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module | x-ray diffraction | B | — | — |
| 4FK5 | Structure of the saga UBP8(S144N)/SGF11/SUS1/SGF73 dub module | x-ray diffraction | B | — | — |
| 4MBE | Sac3:Sus1:Cdc31:Nup1 complex | x-ray diffraction | C, F | — | — |
| 4MBE | SAC3:SUS1:CDC31:NUP1 complex | x-ray diffraction | C, F | — | — |
| 4WA6 | Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution | x-ray diffraction | B, F | — | — |
| 4WA6 | Structure of yeast saga dubm with SGF73 N59D mutant at 2.36 ångströms resolution | x-ray diffraction | B, F | — | — |
| 4ZUX | Saga dub module UBP8/SGF11/SUS1/SGF73 bound to ubiqitinated nucleosome | x-ray diffraction | V, a, f, k | — | — |
| 6AQR | SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin | x-ray diffraction | B | — | 1 (best 0.85) |
| 6AQR | Saga dub module UBP8(C146A)/SGF11/SUS1/SGF73 bound to monoubiquitin | x-ray diffraction | B | — | — |
| 6T9L | SAGA DUB module bound to a ubiqitinated nucleosome | electron microscopy | L | — | 3 (best 0.83) |
| 6T9L | Saga dub module bound to a ubiqitinated nucleosome | electron microscopy | L | — | — |
| Q6WNK7 | AlphaFold monomer V2.0 prediction for transcription and mRNA export factor SUS1 (Q6WNK7) | predicted | A | — | — |
Experiment against prediction
- 4FJC chain F against the predicted model Q6WNK7: TM-score 0.95, RMSD 0.84 Å
- 4FJC chain F against the predicted model Q6WNK7: TM-score 0.95, RMSD 0.84 Å
- 3KIK chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.25 Å
- 3KIK chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.25 Å
- 6AQR chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.27 Å
- 6AQR chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.27 Å
- 3MHS chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.28 Å
- 3MHS chain B against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.28 Å
- 3KIK chain C against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.36 Å
- 3KIK chain C against the predicted model Q6WNK7: TM-score 0.93, RMSD 1.36 Å
Elsewhere
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