UniProt Q6MZV7
Fc fragment of human IgG1 (Q6MZV7)
Fc fragment of human IgG1 (UniProt Q6MZV7): 25 experimental structures on GenesisL1, 8 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q6MZV7
- Protein
- Fc fragment of human IgG1
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 33 · 1 record with a druggable one
Structures
25 records of Q6MZV7 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NSC | Fc DEKK heterodimer variant | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | — |
| 5NSC | Fc dekk heterodimer variant | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | — |
| 5NSG | Fc DEDE homodimer variant | x-ray diffraction | A | NAG, BMA, MAN, FUC, ZN | — |
| 5NSG | Fc dede homodimer variant | x-ray diffraction | A | NAG, BMA, MAN, FUC, ZN | — |
| 5U4Y | IgG Fc bound to 3 helix of the B-domain from Protein A | x-ray diffraction | A, B | NAG, MAN, GAL, FUC | 4 (best 0.38) |
| 5U4Y | IgG Fc bound to 3 helix of the B-domain from protein a | x-ray diffraction | A, B | NAG, MAN, GAL, FUC | — |
| 5U52 | 2 helix minimized version of the B-domain from Protein A (Z34C0 bound to IgG1 Fc (monoclinic form) | x-ray diffraction | A, B | NAG, MAN, GAL, FUC | 4 (best 0.36) |
| 5U52 | 2 helix minimized version of the B-domain from protein a (Z34C0 bound to IGG1 Fc (monoclinic form) | x-ray diffraction | A, B | NAG, MAN, GAL | — |
| 5U66 | Modified single helix from the B-domain of protein a bound to IGG1 Fc | x-ray diffraction | A | NAG, BMA, MAN, GAL | — |
| 5VME | Crystal structure of human IgG1 Fc K248E, T437R mutant | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 5VME | Crystal structure of human IGG1 Fc K248E, T437R mutant | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 6CHF | Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | 2 (best 0.33) |
| 6CHF | Crystal structure of a Fc fragment lala mutant (L234A, L235A) of human IGG1 (crystal form 1) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 6CJC | Crystal structure of a Fc fragment lala mutant (L234A, L235A) of human IGG1 (crystal form 3) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC, CL | 2 (best 0.34) |
| 6CJC | Crystal structure of a Fc fragment lala mutant (L234A, L235A) of human IGG1 (crystal form 3) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC, CL | — |
| 6CJX | Crystal structure of a Fc fragment lala mutant (L234A, L235A) of human IGG1 (crystal form 2) | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 6N9T | Structure of a peptide-based photo-affinity cross-linker with Herceptin Fc | x-ray diffraction | A, B | NAG, BMA, MAN, FUL | — |
| 6N9T | Structure of a peptide-based photo-affinity cross-linker with herceptin Fc | x-ray diffraction | A, B | NAG, BMA, MAN, FUL | — |
| 6P6D | Human IGG1 Fc fragment, C239 insertion mutant | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 6P6D | Human IGG1 Fc fragment, C239 insertion mutant | x-ray diffraction | A, B | NAG, BMA, MAN, FUC | — |
| 7LF5 | Structure of Hyperglycosylated Human IgG1 Fc (Fc267) | x-ray diffraction | A | NAG, BMA, MAN, GAL | 1 (best 0.36) |
| 7LF5 | Structure of hyperglycosylated human IGG1 Fc (FC267) | x-ray diffraction | A | NAG, BMA, MAN, GAL | — |
| 7LF9 | Structure of hyperglycosylated human IGG1 Fc (FC329) | x-ray diffraction | A, B | NAG, BMA, MAN, GAL, FUC | — |
| 7LFN | Structure of hyperglycosylated human IGG1 Fc (FC267_329) | x-ray diffraction | A, B | NAG, FUC, BMA, MAN, GAL | — |
| 7RHO | Human IgG1 Fc fragment, hinge-free, expressed in E. coli | x-ray diffraction | A, B, D, E, F, G, J, K | — | 20 (best 0.53) |
Ligands
- MAN · alpha-D-mannopyranose · in 24 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 24 records
- BMA · beta-D-mannopyranose · in 20 records
- FUC · alpha-L-fucopyranose · in 18 records
- GAL · beta-D-galactopyranose · in 11 records
- CL · Chloride ion · in 2 records
- FUL · beta-L-fucopyranose · in 2 records
- ZN · Zinc ion · in 2 records
Elsewhere
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