UniProt Q6J8I9
Lens fiber major intrinsic protein (Q6J8I9)
Lens fiber major intrinsic protein (UniProt Q6J8I9): 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6J8I9
- Protein
- Lens fiber major intrinsic protein
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 6 · 2 records with a druggable one
Structures
9 records of Q6J8I9 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SOR | Aquaporin-0 membrane junctions reveal the structure of a closed water pore | electron crystallography | A | — | — |
| 1SOR | Aquaporin-0 membrane junctions reveal the structure of a closed water pore | electron crystallography | A | — | — |
| 2B6O | Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) at 1.9A resolution, in a… | electron crystallography | A | — | — |
| 2B6O | Electron crystallographic structure of lens aquaporin-0 (AQP0) (lens mip) at 1.9A resolution, in a… | electron crystallography | A | — | — |
| 3M9I | Electron crystallographic structure of lens Aquaporin-0 (AQP0) (lens MIP) in E. coli polar lipids | electron crystallography | A | — | — |
| 3M9I | Electron crystallographic structure of lens aquaporin-0 (AQP0) (lens mip) in E. COLI polar lipids | electron crystallography | A | — | — |
| 8SJX | Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (2SM:1Chol) | electron crystallography | A | HWP, CLR | 2 (best 0.50) |
| 8SJY | Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (1SM:2Chol) | electron crystallography | A | HWP, CLR | 2 (best 0.54) |
| Q6J8I9 | AlphaFold monomer V2.0 prediction for lens fiber major intrinsic protein (Q6J8I9) | predicted | A | — | 2 (best 0.44) |
Ligands
Experiment against prediction
- 8SJY chain A against the predicted model Q6J8I9: TM-score 0.99, RMSD 0.67 Å
- 3M9I chain A against the predicted model Q6J8I9: TM-score 0.99, RMSD 0.69 Å
- 3M9I chain A against the predicted model Q6J8I9: TM-score 0.99, RMSD 0.69 Å
- 8SJX chain A against the predicted model Q6J8I9: TM-score 0.99, RMSD 0.73 Å
- 2B6O chain A against the predicted model Q6J8I9: TM-score 0.97, RMSD 0.97 Å
- 2B6O chain A against the predicted model Q6J8I9: TM-score 0.97, RMSD 0.97 Å
- 1SOR chain A against the predicted model Q6J8I9: TM-score 0.97, RMSD 1.09 Å
- 1SOR chain A against the predicted model Q6J8I9: TM-score 0.97, RMSD 1.09 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.