GL1X · GenesisL1 explorer

Ligand · HWP

HWP · [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate

HWP, [(E,2S,3R)-2-(hexadecanoylamino)-3-oxidanyl-octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate (C39 H79 N2 O6 P, 703.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its…

Component
HWP
Formula
C39 H79 N2 O6 P
Class
ligand
Structures
2
PDB entries
2

Binding sites

HWP in 2 structures; the first of them:

  • 8SJX · Structure of lens aquaporin-0 array in sphingomyelin/cholesterol bilayer (2SM:1Chol) · HWP A301 · binds ILE193, PHE198
  • 7FDV · Cryo-EM structure of the human cholesterol transporter ABCG1 in complex with cholesterol · HWP A702 · binds SER420, PHE464, PHE467, LEU475, GLN563, PHE567, VAL568, ILE574

Residues it binds most

PHE 7, LEU 6, VAL 6, ILE 6, ALA 4, SER 3, ARG 2, GLN 2, TRP 2, TYR 2 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol
  • ATP · Adenosine-5'-triphosphate

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