UniProt Q64373
Bcl-2-like protein 1 (Q64373)
Bcl-2-like protein 1 (UniProt Q64373): 29 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q64373
- Protein
- Bcl-2-like protein 1
- Experimental structures
- 29
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
30 records of Q64373 in the MolNFT archive: 29 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PQ0 | Crystal structure of mouse Bcl-xl | x-ray diffraction | A | — | — |
| 1PQ0 | Crystal structure of mouse BCL-xl | x-ray diffraction | A | — | — |
| 1PQ1 | Crystal structure of Bcl-xl/Bim | x-ray diffraction | A | — | — |
| 1PQ1 | Crystal structure of BCL-XL/BIM | x-ray diffraction | A | — | — |
| 2BZW | The crystal structure of BCL-XL in complex with full-length BAD | x-ray diffraction | A | — | — |
| 2BZW | The crystal structure of BCL-xl in complex with full-length bad | x-ray diffraction | A | — | — |
| 3IHC | Crystal structure of mouse Bcl-xl (wt) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IHC | Crystal structure of mouse BCL-xl (wt) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IHD | Crystal structure of mouse Bcl-xl mutant (Y101A) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IHD | Crystal structure of mouse BCL-xl mutant (Y101A) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IHE | Crystal structure of mouse Bcl-xl mutant (F105A) at pH 6.0 | x-ray diffraction | A | — | — |
| 3IHE | Crystal structure of mouse BCL-xl mutant (F105A) at pH 6.0 | x-ray diffraction | A | — | — |
| 3IHF | Crystal structure of mouse Bcl-xl mutant (R139A) at pH 5.0 | x-ray diffraction | A, B, C, D | — | — |
| 3IHF | Crystal structure of mouse BCL-xl mutant (R139A) at pH 5.0 | x-ray diffraction | A, B, C, D | — | — |
| 3IIG | Crystal structure of mouse Bcl-xl mutant (F105A) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IIG | Crystal structure of mouse BCL-xl mutant (F105A) at pH 5.0 | x-ray diffraction | A | — | — |
| 3IIH | Crystal structure of mouse Bcl-xl (wt) at pH 6.0 | x-ray diffraction | A | — | — |
| 3IIH | Crystal structure of mouse BCL-xl (wt) at pH 6.0 | x-ray diffraction | A | — | — |
| 3ILB | Crystal structure of mouse Bcl-xl mutant (R139A) at pH 6.0 | x-ray diffraction | A, N | — | — |
| 3ILB | Crystal structure of mouse BCL-xl mutant (R139A) at pH 6.0 | x-ray diffraction | A, N | — | — |
| 3ILC | Crystal structure of mouse Bcl-xl mutant (Y101A) at pH 6.0 | x-ray diffraction | A | — | — |
| 3ILC | Crystal structure of mouse BCL-xl mutant (Y101A) at pH 6.0 | x-ray diffraction | A | — | — |
| 4YJ4 | Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and… | x-ray diffraction | A | — | — |
| 4YJ4 | Crystal structure of BCL-xl in complex with the bim BH3 domain containing ILE155-to-arg and… | x-ray diffraction | A | — | — |
| 4YK9 | Complex structure of BCL-XL and mutated BIM BH3 domain | x-ray diffraction | A, F | — | — |
| 4YK9 | Complex structure of BCL-xl and mutated bim BH3 domain | x-ray diffraction | A, F | — | — |
| 5C3G | Crystal structure of BCL-xl bound to bim-mm | x-ray diffraction | A | — | — |
| 7WJH | Crystal structure of Bcl-xL bound to the BH3 domain of human Pxt1 | x-ray diffraction | A | SO4, MG | 2 (best 0.52) |
| 7Y99 | Crystal Structure Analysis of cp2 bound BCLxl | x-ray diffraction | A | IQ8 | — |
| Q64373 | AlphaFold monomer V2.0 prediction for BCL-2-like protein 1 (Q64373) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4YK9 chain F against the predicted model Q64373: TM-score 0.98, RMSD 0.79 Å
- 4YK9 chain F against the predicted model Q64373: TM-score 0.98, RMSD 0.79 Å
- 4YK9 chain A against the predicted model Q64373: TM-score 0.98, RMSD 0.80 Å
- 4YK9 chain A against the predicted model Q64373: TM-score 0.98, RMSD 0.80 Å
- 2BZW chain A against the predicted model Q64373: TM-score 0.97, RMSD 0.94 Å
- 2BZW chain A against the predicted model Q64373: TM-score 0.97, RMSD 0.94 Å
- 1PQ1 chain A against the predicted model Q64373: TM-score 0.95, RMSD 1.39 Å
- 1PQ1 chain A against the predicted model Q64373: TM-score 0.95, RMSD 1.39 Å
- 4YJ4 chain A against the predicted model Q64373: TM-score 0.93, RMSD 1.47 Å
- 4YJ4 chain A against the predicted model Q64373: TM-score 0.93, RMSD 1.47 Å
Elsewhere
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