MolNFT v1 · #67369 · protein

Crystal structure of mouse BCL-xl mutant (F105A) at pH 5.0

3IIG · BCL-2-like protein 1: “Crystal structure of mouse BCL-xl mutant (F105A) at pH 5.0”. X-ray diffraction, 1 pocket (best druggability 0.41). MolNFT v1 #67369 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3IIG
Type: protein
Length: 141 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BCL-2-like protein 1
UniProt: Q64373
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BCL-2-like protein 1	protein	141	76% helix, 0% strand	Q64373

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	114	0.41	0.76	25	empty

Compared structures

3IIG · Crystal structure of mouse Bcl-xl mutant (F105A) at pH 5.0 · the same entry in another collection · chain A against A, TM-score 1.00
Q64373 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 1 (Q64373) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q64373
Elsewhere: RCSB PDB 3IIG · PDBe 3IIG · UniProt Q64373

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