UniProt Q5T0W9
Protein FAM83B (Q5T0W9)
Protein FAM83B (UniProt Q5T0W9): 18 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q5T0W9
- Protein
- Protein FAM83B
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 3 · 1 record with a druggable one
Structures
19 records of Q5T0W9 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LZK | Structure of the domain of unknown function DUF1669 from human FAM83B | x-ray diffraction | A, B | IOD | — |
| 5LZK | Structure of the domain of unknown function DUF1669 from human FAM83B | x-ray diffraction | A, B | IOD | — |
| 5QHI | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal… | x-ray diffraction | A, B | IOD, GOJ | — |
| 5QHI | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A, B | IOD, GOJ | — |
| 5QHJ | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal… | x-ray diffraction | A, B | IOD, GOV | 2 (best 0.55) |
| 5QHJ | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A, B | IOD, GOV | — |
| 5QHK | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal… | x-ray diffraction | A, B | IOD, GOY | — |
| 5QHK | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A, B | IOD, GOY | — |
| 5QHL | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A, B | IOD, GQ7 | — |
| 5QHM | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal… | x-ray diffraction | A | GQA | — |
| 5QHM | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GQA | — |
| 5QHN | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | — | — |
| 5QHO | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GOY | — |
| 5QHP | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GQM | — |
| 5QHQ | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GQP | — |
| 5QHR | PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal… | x-ray diffraction | A | GQS | 1 (best 0.35) |
| 5QHR | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GQS | — |
| 5QHS | Pandda analysis group deposition of models with modelled events (E.G. bound ligands) -- crystal… | x-ray diffraction | A | GQV | — |
| Q5T0W9 | AlphaFold monomer V2.0 prediction for protein FAM83B (Q5T0W9) | predicted | A | — | — |
Ligands
- IOD · Iodide ion · in 9 records
- GOY · di(piperidin-1-yl)methanone · in 3 records
- GOJ · ethyl 1~{H}-pyrazole-4-carboxylate · in 2 records
- GOV · (2S)-1-{[(2H-1,3-benzodioxol-5-yl)methyl]amino}propan-2-ol · in 2 records
- GQA · 1-methyl-3-oxidanyl-pyridine-2-thione · in 2 records
- GQS · N-(3-fluorophenyl)-5-methyl-1,3,4-thiadiazol-2-amine · in 2 records
- GQ7 · [5-(4-aminophenyl)furan-2-yl]methanol · in 1 record
- GQM · 5-methoxy-2-(1~{H}-pyrazol-3-yl)phenol · in 1 record
- GQP · 1-[(4-fluorophenyl)methyl]benzimidazole · in 1 record
- GQV · 1-methyl-3-oxidanyl-pyridin-2-one · in 1 record
Experiment against prediction
- 5QHM chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 0.88 Å
- 5QHM chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 0.88 Å
- 5LZK chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 1.05 Å
- 5LZK chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 1.05 Å
- 5QHP chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 0.89 Å
- 5QHQ chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 0.89 Å
- 5QHI chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 1.06 Å
- 5QHI chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 1.06 Å
- 5QHS chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 0.89 Å
- 5QHK chain A against the predicted model Q5T0W9: TM-score 0.98, RMSD 1.06 Å
Elsewhere
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