UniProt Q59961
DNA topoisomerase 4 subunit B,ParE30-ParC55 fused topo IV from S. pneumoniae (Q59961)
DNA topoisomerase 4 subunit B,ParE30-ParC55 fused topo IV from S. pneumoniae (UniProt Q59961), EC 5.99.1.3: 35 experimental structures on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, pockets, druggability and 3D…
- UniProt
- Q59961
- Protein
- DNA topoisomerase 4 subunit B,ParE30-ParC55 fused topo IV from S. pneumoniae
- EC
- 5.99.1.3
- Experimental structures
- 35
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 17 · 1 record with a druggable one
Structures
35 records of Q59961 in the MolNFT archive: 35 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FOE | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | x-ray diffraction | C, D | — | — |
| 3FOE | Structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases | x-ray diffraction | C, D | — | — |
| 3FOF | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | x-ray diffraction | C, D | — | — |
| 3FOF | Structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases | x-ray diffraction | C, D | — | — |
| 3K9F | Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | x-ray diffraction | C, D | — | — |
| 3K9F | Detailed structural insight into the quinolone-DNA cleavage complex of type iia topoisomerases | x-ray diffraction | C, D | — | — |
| 3KSA | Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (cleaved form) | x-ray diffraction | C, D | — | — |
| 3KSA | Detailed structural insight into the DNA cleavage complex of type iia topoisomerases (cleaved form) | x-ray diffraction | C, D | — | — |
| 3KSB | Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (re-sealed… | x-ray diffraction | C, D | — | — |
| 3KSB | Detailed structural insight into the DNA cleavage complex of type iia topoisomerases (re-sealed… | x-ray diffraction | C, D | — | — |
| 3LTN | Inhibitor-stabilized topoisomerase IV-DNA cleavage complex (S. pneumoniae) | x-ray diffraction | C, D | — | — |
| 3LTN | Inhibitor-stabilized topoisomerase IV-DNA cleavage complex (S. pneumoniae) | x-ray diffraction | C, D | — | — |
| 3RAD | Quinolone(Clinafloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 3RAD | QUINOLONE(CLINAFLOXACIN)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 3RAE | Quinolone(Levofloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 3RAE | QUINOLONE(LEVOFLOXACIN)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 3RAF | Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 3RAF | Quinazolinedione-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 4JUO | A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space… | x-ray diffraction | C | — | — |
| 4JUO | A low-resolution three-gate structure of topoisomerase IV from streptococcus pneumoniae in space… | x-ray diffraction | C | — | — |
| 4KOE | Quinolone(Trovafloxacin)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 4KOE | QUINOLONE(TROVAFLOXACIN)-DNA cleavage complex of type IV topoisomerase from S. pneumoniae | x-ray diffraction | C, D | — | — |
| 4KPE | Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate | x-ray diffraction | C, D | — | — |
| 4KPE | Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate | x-ray diffraction | C, D | — | — |
| 4KPF | Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate | x-ray diffraction | C, D | — | — |
| 4KPF | Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate | x-ray diffraction | C, D | — | — |
| 4Z3O | Quinolone(Moxifloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | x-ray diffraction | A, B | MG, MFX | 17 (best 0.79) |
| 4Z3O | QUINOLONE(MOXIFLOXACIN)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 4Z4Q | QUINAZOLINEDIONE(PD 0305970)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 4Z53 | Quinolone(Trovafloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 4Z53 | QUINOLONE(TROVAFLOXACIN)-DNA cleavage complex of topoisomerase IV from S. pneumoniae | x-ray diffraction | A, B | — | — |
| 5J5P | AMP-pnp-stabilized ATPase domain of topoisomerase IV from streptococcus pneumoniae, complex type I | x-ray diffraction | A, B | — | — |
| 5J5Q | AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type II | x-ray diffraction | A, B, C, D | ANP, MG | — |
| 5J5Q | AMP-pnp-stabilized ATPase domain of topoisomerase IV from streptococcus pneumoniae, complex type II | x-ray diffraction | A, B, C, D | — | — |
| Q59961 | AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit B (Q59961) | — | — | — |
Ligands
Elsewhere
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