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Ligand · AF5

AF5 · (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid

AF5, (7aR,8R)-8-amino-4-cyclopropyl-12-fluoro-1-oxo-4,7,7a,8,9,10-hexahydro-1H-pyrrolo[1',2':1,7]azepino[2,3-h]quinoline-2-carboxylic acid (C20 H20 F N3 O3, 369.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
AF5
Formula
C20 H20 F N3 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

AF5 in 2 structures; the first of them:

  • 4KPE · Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site… · AF5 F101 · binds SER79, ARG117, ARG456, GLY457, GLU475, DT15, DC4, DA5 and 1 more
  • 4KPE · Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site… · AF5 F101 · binds SER79, ARG117, ARG456, GLY457, GLU475, DT15, DC4, DA5 and 1 more

Residues it binds most

ARG 4, DA 4, DT 4, GLU 4, GLY 4, SER 4, DC 2, DG 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

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