LFX · (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

Binding sites

LFX in 3 structures; the first of them:

• 4Z2D · Quinolone(Levofloxacin)-DNA cleavage complex of gyrase from S. pneumoniae · LFX F102 · binds ARG456, GLY457, GLU475, SER81, DG1, DC4, DA5, DT15
• 5BTI · Crystal structure of a topoisomerase II complex · LFX E101 · binds SER90, SER91, ARG482, GLY483, THR500, GLU501, PTR129, DT10 and 7 more
• 7B8T · Levofloxacin bound structure of bacterial efflux pump. · LFX C901 · binds PHE136, VAL139, GLN176, PHE178, ILE277, TYR327, PHE610, VAL612 and 2 more

Residues it binds most

DA 4, DT 4, SER 4, ARG 4, PHE 1, DC 4, DG 4, GLU 4, GLY 4, PTR 2 (residue and the binding sites it lines).

Found with

• MG · Magnesium ion