GL1X · GenesisL1 explorer

Ligand · MFX

MFX · 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

MFX, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (C21 H24 F N3 O4, 401.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (3 PDB…

Component
MFX
Formula
C21 H24 F N3 O4
Class
ligand
Structures
3
PDB entries
3

Binding sites

MFX in 3 structures; the first of them:

  • 4Z2C · Quinolone(Moxifloxacin)-DNA cleavage complex of gyrase from S. pneumoniae · MFX F101 · binds ARG456, GLY457, GLU475, SER81, DG1, DC4, DA5, DT15
  • 4Z3O · Quinolone(Moxifloxacin)-DNA cleavage complex of topoisomerase IV from S. pneumoniae · MFX F101 · binds ARG1117, ARG456, GLY457, GLU475, SER1079, DT15, DC4, DA5 and 1 more
  • 5BTA · Crystal structure of a topoisomerase II complex · MFX G101 · binds ARG128, PTR129, SER90, SER91, ARG482, GLY483, THR500, GLU501 and 8 more

Residues it binds most

DA 6, DT 6, ARG 6, SER 6, GLU 6, GLY 6, DC 5, DG 5, PTR 2, THR 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.