UniProt Q4H132
Sodium/potassium-transporting ATPase subunit alpha (Q4H132)
Sodium/potassium-transporting ATPase subunit alpha (UniProt Q4H132): 62 experimental structures on GenesisL1, 11 ligands bound, 306 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q4H132
- Protein
- Sodium/potassium-transporting ATPase subunit alpha
- Experimental structures
- 62
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 306 · 17 records with a druggable one
Structures
62 records of Q4H132 in the MolNFT archive: 62 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ZXE | Crystal structure of the sodium - potassium pump in the E2.2K+.Pi state | x-ray diffraction | A | — | — |
| 2ZXE | Crystal structure of the sodium - potassium pump in the E2.2K+.PI state | x-ray diffraction | A | — | — |
| 3A3Y | Crystal structure of the sodium-potassium pump with bound potassium and ouabain | x-ray diffraction | A | — | — |
| 3A3Y | Crystal structure of the sodium-potassium pump with bound potassium and ouabain | x-ray diffraction | A | — | — |
| 5AVQ | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVQ | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVR | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVR | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVS | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, K, TL, CLR | 16 (best 0.77) |
| 5AVS | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVT | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, K, TL, CLR | 16 (best 0.78) |
| 5AVT | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVU | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVU | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVV | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVV | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVW | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVW | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVX | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVX | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVY | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, TL, K, CLR | 17 (best 0.77) |
| 5AVY | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AVZ | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, TL, K, CLR | 16 (best 0.77) |
| 5AVZ | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW0 | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, TL, K, CLR | 16 (best 0.78) |
| 5AW0 | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW1 | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW1 | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW2 | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW2 | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW3 | Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW3 | Kinetics by X-ray crystallography: tl+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW4 | Kinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW4 | Kinetics by X-ray crystallography: rb+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW5 | Kinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW5 | Kinetics by X-ray crystallography: rb+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW6 | Kinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | MF4, MG, K, RB, CLR | 15 (best 0.77) |
| 5AW6 | Kinetics by X-ray crystallography: rb+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW7 | Kinetics by X-ray crystallography: Rb+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW7 | Kinetics by X-ray crystallography: rb+-substitution of bound K+ in the E2.MGF42-.2K+ crystal after… | x-ray diffraction | A | — | — |
| 5AW8 | Kinetics by X-ray crystallography: E2.MgF42-.2RB+ crystal | x-ray diffraction | A | MF4, MG, RB, CLR | 16 (best 0.78) |
| 5AW8 | Kinetics by X-ray crystallography: E2.MGF42-.2RB+ crystal | x-ray diffraction | A | — | — |
| 5AW9 | Kinetics by X-ray crystallography: native E2.MgF42-.2K+ crystal for Rb+ bound crystals | x-ray diffraction | A | MF4, MG, K, CLR | 16 (best 0.79) |
| 5AW9 | Kinetics by X-ray crystallography: native E2.MGF42-.2K+ crystal for rb+ bound crystals | x-ray diffraction | A | — | — |
| 7WYU | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP | electron microscopy | A, C | MG, NA, ATP, CLR, PCW | 20 (best 0.78) |
| 7WYU | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by ATP | electron microscopy | A, C | MG, NA, ATP, CLR, PCW | — |
| 7WYV | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mM Mg2+ | electron microscopy | A, C | MG, NA, ATP, CLR, PCW | 20 (best 0.77) |
| 7WYV | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mm MG2+ | electron microscopy | A, C | MG, NA, ATP, CLR, PCW | — |
| 7WYW | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate | electron microscopy | A, C | MG, CLR, PCW | 19 (best 0.77) |
| 7WYW | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by inorganic phosphate | electron microscopy | A, C | MG, CLR, PCW | — |
| 7WYX | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with istaroxime | electron microscopy | A, C | MG, NA, ATP, 7Q2, CLR, PCW | 20 (best 0.79) |
| 7WYX | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by ATP with istaroxime | electron microscopy | A, C | MG, NA, ATP, 7Q2, CLR, PCW | — |
| 7WYY | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with istaroxime | electron microscopy | A, C | MG, 7Q2, CLR, PCW | 20 (best 0.78) |
| 7WYY | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by inorganic phosphate with istaroxime | electron microscopy | A, C | MG, 7Q2, CLR, PCW | — |
| 7WYZ | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP with ouabain | electron microscopy | A, C | MG, NA, OBN, CLR, PCW | 20 (best 0.78) |
| 7WYZ | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by ATP with ouabain | electron microscopy | A, C | MG, NA, OBN, CLR, PCW | — |
| 7WZ0 | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with ouabain | electron microscopy | A, C | MG, OBN, CLR, PCW | 20 (best 0.78) |
| 7WZ0 | Cryo-EM structure of NA+,K+-ATPase in the E2P state formed by inorganic phosphate with ouabain | electron microscopy | A, C | MG, OBN, CLR, PCW | — |
| 7Y45 | Cryo-EM structure of the NA+,K+-ATPase in the E2.2K+ state | electron microscopy | C, A | K, CLR, PCW | — |
| 7Y46 | Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state after addition of ATP | electron microscopy | C, A | ATP, K, CLR, PCW | 19 (best 0.77) |
2 records more on the page itself.
Ligands
- CLR · Cholesterol · in 26 records
- MG · Magnesium ion · in 23 records
- PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 18 records
- K · Potassium ion · in 10 records
- ATP · Adenosine-5'-triphosphate · in 8 records
- MF4 · Tetrafluoromagnesate(2-) · in 8 records
- NA · Sodium ion · in 8 records
- TL · Thallium (I) ion · in 5 records
- 7Q2 · (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10, 13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione · in 4 records
- OBN · Ouabain · in 4 records
- RB · Rubidium ion · in 2 records
Elsewhere
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