UniProt Q3E7C1
General transcription and DNA repair factor IIH subunit TFB5 (Q3E7C1)
General transcription and DNA repair factor IIH subunit TFB5 (UniProt Q3E7C1): 50 experimental structures and 1 predicted model on GenesisL1, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q3E7C1
- Protein
- General transcription and DNA repair factor IIH subunit TFB5
- Experimental structures
- 50
- Predicted models
- 1
- Pockets
- 14 · 14 records with a druggable one
Structures
51 records of Q3E7C1 in the MolNFT archive: 50 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DGP | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | x-ray diffraction | B | — | — |
| 3DGP | Crystal structure of the complex between TFB5 and the C-terminal domain of TFB2 | x-ray diffraction | B | — | — |
| 3DOM | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | x-ray diffraction | B, D | — | — |
| 3DOM | Crystal structure of the complex between TFB5 and the C-terminal domain of TFB2 | x-ray diffraction | B, D | — | — |
| 5FMF | the P-lobe of RNA polymerase II pre-initiation complex | electron microscopy | X | — | — |
| 5FMF | The P-lobe of RNA polymerase II pre-initiation complex | electron microscopy | X | — | — |
| 5OQJ | Structure of yeast transcription pre-initiation complex with tfiih | electron microscopy | 5 | — | — |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | 5 | — | — |
| 5OQM | Structure of yeast transcription pre-initiation complex with tfiih and core mediator | electron microscopy | 5 | — | — |
| 5SVA | Mediator-RNA Polymerase II Pre-Initiation Complex | electron microscopy | b | — | — |
| 5SVA | Mediator-RNA polymerase II pre-initiation complex | electron microscopy | b | — | — |
| 6GYM | Structure of a yeast closed complex with distorted DNA (CCdist) | electron microscopy | 5 | — | — |
| 6GYM | Structure of a yeast closed complex with distorted DNA (ccdist) | electron microscopy | 5 | — | — |
| 7K01 | Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex | electron microscopy | 5 | — | 1 (best 0.61) |
| 7K01 | Structure of tfiih in TFIIH/RAD4-RAD23-RAD33 DNA opening complex | electron microscopy | 5 | — | — |
| 7K04 | Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening | electron microscopy | 5 | — | — |
| 7K04 | Structure of TFIIH/RAD4-RAD23-RAD33/DNA in DNA opening | electron microscopy | 5 | — | — |
| 7M2U | Nucleotide Excision Repair complex TFIIH Rad4-33 | electron microscopy | 5 | — | 1 (best 0.63) |
| 7M2U | Nucleotide excision repair complex tfiih RAD4-33 | electron microscopy | 5 | — | — |
| 7ML0 | RNA polymerase II pre-initiation complex (PIC1) | electron microscopy | 5 | — | 1 (best 0.76) |
| 7ML0 | RNA polymerase II pre-initiation complex (PIC1) | electron microscopy | 5 | — | — |
| 7ML1 | RNA polymerase II pre-initiation complex (PIC2) | electron microscopy | 5 | — | — |
| 7ML1 | RNA polymerase II pre-initiation complex (PIC2) | electron microscopy | 5 | — | — |
| 7ML2 | RNA polymerase II pre-initiation complex (PIC3) | electron microscopy | 5 | — | 1 (best 0.77) |
| 7ML2 | RNA polymerase II pre-initiation complex (PIC3) | electron microscopy | 5 | — | — |
| 7ML3 | General transcription factor TFIIH (weak binding) | electron microscopy | 5 | — | 1 (best 0.77) |
| 7ML3 | General transcription factor tfiih (weak binding) | electron microscopy | 5 | — | — |
| 7ML4 | RNA polymerase II initially transcribing complex (ITC) | electron microscopy | 5 | — | — |
| 7ML4 | RNA polymerase II initially transcribing complex (itc) | electron microscopy | 5 | — | — |
| 7O4I | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | electron microscopy | 5 | — | — |
| 7O4I | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | electron microscopy | 5 | — | — |
| 7O4J | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | electron microscopy | 5 | — | 1 (best 0.80) |
| 7O4J | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | electron microscopy | 5 | — | — |
| 7O4K | Yeast TFIIH in the contracted state within the pre-initiation complex | electron microscopy | 5 | — | 1 (best 0.80) |
| 7O4K | Yeast tfiih in the contracted state within the pre-initiation complex | electron microscopy | 5 | — | — |
| 7O4L | Yeast TFIIH in the expanded state within the pre-initiation complex | electron microscopy | 5 | — | 1 (best 0.80) |
| 7O4L | Yeast tfiih in the expanded state within the pre-initiation complex | electron microscopy | 5 | — | — |
| 7O72 | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | electron microscopy | 5 | — | 1 (best 0.82) |
| 7O72 | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | electron microscopy | 5 | — | — |
| 7O73 | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | electron microscopy | 5 | — | 1 (best 0.79) |
| 7O73 | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | electron microscopy | 5 | — | — |
| 7O75 | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | electron microscopy | 5 | — | 1 (best 0.80) |
| 7O75 | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | electron microscopy | 5 | — | — |
| 7ZS9 | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) | electron microscopy | 5 | — | 1 (best 0.80) |
| 7ZSA | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP… | electron microscopy | 5 | — | 1 (best 0.77) |
| 7ZSB | Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP… | electron microscopy | 5 | — | 1 (best 0.80) |
| 8UMH | Consensus map of PICdeltaTFIIK form2 | electron microscopy | 5 | — | — |
| 8UMI | consensus map of PICdeltaTFIIK form1 | electron microscopy | 5 | — | — |
| 8UOQ | Composite map of PIC_delta_TFIIK form2 | electron microscopy | 5 | — | — |
| 8UOT | Composite map of PICdeltaTFIIK form1 | electron microscopy | 5 | — | — |
| Q3E7C1 | AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih subunit TFB5… | predicted | A | — | — |
Experiment against prediction
- 3DOM chain B against the predicted model Q3E7C1: TM-score 0.93, RMSD 0.85 Å
- 3DOM chain B against the predicted model Q3E7C1: TM-score 0.93, RMSD 0.85 Å
- 5SVA chain b against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 5SVA chain b against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 3DGP chain B against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 3DGP chain B against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 5FMF chain X against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 5FMF chain X against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.23 Å
- 5OQJ chain 5 against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.06 Å
- 5OQM chain 5 against the predicted model Q3E7C1: TM-score 0.91, RMSD 1.06 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.