MolNFT v1 · #182240 · protein + DNA
General transcription factor tfiih (weak binding)
7ML3: “General transcription factor tfiih (weak binding)”. Electron microscopy, 2 ligands (SF4, ZN). MolNFT v1 #182240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7ML3
- Type
- protein + DNA
- Length
- 3,028 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A7I9BTI9, A0A6A5Q2X3, A0A6A5Q1C1, A0A7I9C5C2, A0A7I9FQL5, Q3E7C1, Q00578
- Ligands
- SF4, ZN
Structure
electron microscopy · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 3 | — | protein | 138 | — | A0A7I9BTI9 |
| 2 | — | protein | 460 | — | A0A6A5Q2X3 |
| 0 | — | protein | 754 | — | A0A6A5Q1C1 |
| 1 | — | protein | 367 | — | — |
| 4 | — | protein | 284 | — | A0A7I9C5C2 |
| 6 | — | protein | 351 | — | A0A7I9FQL5 |
| 5 | — | protein | 66 | — | Q3E7C1 |
| 7 | — | protein | 548 | — | Q00578 |
| N | — | dna | 30 | — | — |
| T | — | dna | 30 | — | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7ML3 · General transcription factor TFIIH (weak binding) · the same entry in another collection · chain N against N, TM-score 1.00
- Q00578 · AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih… · a predicted model of the same protein · chain 7 against A, TM-score 0.87
- Q3E7C1 · AlphaFold monomer V2.0 prediction for general transcription and DNA repair factor iih… · a predicted model of the same protein · chain 5 against A, TM-score 0.76
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7I9BTI9
- Every structure of UniProt A0A6A5Q2X3
- Every structure of UniProt A0A6A5Q1C1
- Every structure of UniProt A0A7I9C5C2
- Every structure of UniProt A0A7I9FQL5
- Every structure of UniProt Q3E7C1
- Every structure of UniProt Q00578
- Elsewhere: RCSB PDB 7ML3 · PDBe 7ML3 · UniProt A0A7I9BTI9 · UniProt A0A6A5Q2X3 · UniProt A0A6A5Q1C1 · UniProt A0A7I9C5C2 · UniProt A0A7I9FQL5 · UniProt Q3E7C1 · UniProt Q00578
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