UniProt Q15717
ELAV-like protein 1 (Q15717)
ELAV-like protein 1 (UniProt Q15717): 20 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15717
- Protein
- ELAV-like protein 1
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 1 record with a druggable one
Structures
21 records of Q15717 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3HI9 | The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE)… | x-ray diffraction | A, B, C, D | — | — |
| 3HI9 | The X-ray crystal structure of the first RNA recognition motif (RRM1) of the au-rich element (are)… | x-ray diffraction | A, B, C, D | — | — |
| 4ED5 | Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | x-ray diffraction | A, B | — | — |
| 4ED5 | Crystal structure of the two N-terminal rrm domains of hur complexed with RNA | x-ray diffraction | A, B | — | — |
| 4EGL | Crystal structure of two tandem RNA recognition motifs of Human antigen R | x-ray diffraction | A | — | — |
| 4EGL | Crystal structure of two tandem RNA recognition motifs of human antigen R | x-ray diffraction | A | — | — |
| 4FXV | Crystal structure of an ELAV-like protein 1 (ELAVL1) from Homo sapiens at 1.90 A resolution | x-ray diffraction | A, B, C, D | — | — |
| 4FXV | Crystal structure of an elav-like protein 1 (ELAVL1) from homo sapiens at 1.90 a resolution | x-ray diffraction | A, B, C, D | — | — |
| 5SZW | NMR solution structure of the RRM1 domain of the post-transcriptional regulator HuR | solution nmr | A | — | — |
| 5SZW | NMR solution structure of the RRM1 domain of the post-transcriptional regulator hur | solution nmr | A | — | — |
| 6G2K | Structure of HuR RRM3 in complex with RNA (UUUUUU) | x-ray diffraction | A, B, C | SO4 | — |
| 6G2K | Structure of hur RRM3 in complex with RNA (uuuuuu) | x-ray diffraction | A, B, C | SO4 | — |
| 6GC5 | Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM | x-ray diffraction | A, B, C, D | — | 1 (best 0.33) |
| 6GC5 | Molecular basis for au-rich element recognition and dimerization by the hur C-terminal rrm | x-ray diffraction | A, B, C, D | — | — |
| 6GD1 | Structure of HuR RRM3 | x-ray diffraction | A, B | NA | 4 (best 0.72) |
| 6GD1 | Structure of hur RRM3 | x-ray diffraction | A, B | NA | — |
| 6GD2 | Structure of HuR RRM3 in complex with RNA | x-ray diffraction | A, B, C | — | 1 (best 0.32) |
| 6GD2 | Structure of hur RRM3 in complex with RNA | x-ray diffraction | A, B, C | — | — |
| 6GD3 | Structure of HuR RRM3 in complex with RNA (UAUUUA) | x-ray diffraction | A, B, C | NA | 2 (best 0.29) |
| 6GD3 | Structure of hur RRM3 in complex with RNA (uauuua) | x-ray diffraction | A, B, C | NA | — |
| Q15717 | AlphaFold monomer V2.0 prediction for elav-like protein 1 (Q15717) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3HI9 chain A against the predicted model Q15717: TM-score 0.99, RMSD 0.28 Å
- 3HI9 chain A against the predicted model Q15717: TM-score 0.99, RMSD 0.28 Å
- 4FXV chain D against the predicted model Q15717: TM-score 0.99, RMSD 0.35 Å
- 4FXV chain D against the predicted model Q15717: TM-score 0.99, RMSD 0.35 Å
- 3HI9 chain C against the predicted model Q15717: TM-score 0.98, RMSD 0.40 Å
- 3HI9 chain C against the predicted model Q15717: TM-score 0.98, RMSD 0.40 Å
- 6GD2 chain B against the predicted model Q15717: TM-score 0.98, RMSD 0.45 Å
- 6GD2 chain B against the predicted model Q15717: TM-score 0.98, RMSD 0.45 Å
- 6GD1 chain A against the predicted model P0AA25: TM-score 0.57, RMSD 0.39 Å
- 6GD1 chain A against the predicted model P0AA25: TM-score 0.57, RMSD 0.39 Å
Elsewhere
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