MolNFT v1 · #149877 · protein + RNA
Structure of hur RRM3 in complex with RNA (uauuua)
6GD3 · Elav-like protein 1: “Structure of hur RRM3 in complex with RNA (uauuua)”. X-ray diffraction, 1 ligand (NA), 2 pockets (best druggability 0.29). MolNFT v1 #149877 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6GD3
- Type
- protein + RNA
- Length
- 256 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Elav-like protein 1; RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3')
- UniProt
- Q15717
- Ligands
- NA
- Pockets
- 2 · best druggability 0.29
Structure
x-ray diffraction · 4 distinct chains · 26% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Elav-like protein 1 | protein | 83 | 27% helix, 36% strand | Q15717 |
| B | Elav-like protein 1 | protein | 83 | 27% helix, 37% strand | Q15717 |
| C | Elav-like protein 1 | protein | 84 | 26% helix, 37% strand | Q15717 |
| P | RNA (5'-R(P*UP*AP*UP*UP*UP*A)-3') | rna | 6 | — | — |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.29 | 0.73 | 15 | empty |
| 2 | 52 | 0.25 | 0.73 | 11 | empty |
Interfaces
4 interfaces between chains.
- C–P · 635 Ų buried · 14 hydrogen bonds · protein-nucleic
- B–P · 445 Ų buried · 5 hydrogen bonds · protein-nucleic
- A–C · 186 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 45 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15717
- Elsewhere: RCSB PDB 6GD3 · PDBe 6GD3 · UniProt Q15717
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