UniProt Q12834
Cell division cycle protein 20 homolog (Q12834)
Cell division cycle protein 20 homolog (UniProt Q12834): 24 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12834
- Protein
- Cell division cycle protein 20 homolog
- Experimental structures
- 24
- Predicted models
- 1
- Pockets
- 18 · 5 records with a druggable one
Structures
25 records of Q12834 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GGA | Structural Analysis of Human Cdc20 Supports Multi-site Degron Recognition by APC/C | x-ray diffraction | A | — | — |
| 4GGA | Structural analysis of human CDC20 supports multi-site degron recognition by APC/C | x-ray diffraction | A | — | — |
| 4GGC | Structural Analysis of Human Cdc20 Supports Multi-site Degron Recognition by APC/C | x-ray diffraction | A | — | — |
| 4GGC | Structural analysis of human CDC20 supports multi-site degron recognition by APC/C | x-ray diffraction | A | — | — |
| 4GGD | Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. | x-ray diffraction | A, B | — | — |
| 4GGD | Structural analysis of human CDC20 supports multisite degron recognition by APC/C. | x-ray diffraction | A, B | — | — |
| 4N14 | Crystal structure of Cdc20 and apcin complex | x-ray diffraction | A | — | — |
| 4N14 | Crystal structure of CDC20 and apcin complex | x-ray diffraction | A | — | — |
| 5G04 | Structure of the human APC-Cdc20-Hsl1 complex | electron microscopy | R | — | — |
| 5G04 | Structure of the human apc-CDC20-HSL1 complex | electron microscopy | R | — | — |
| 5KHR | Model of human Anaphase-promoting complex/Cyclosome complex (APC15 deletion mutant) in complex with… | electron microscopy | R | — | — |
| 5KHR | Model of human anaphase-promoting COMPLEX/CYCLOSOME complex (APC15 deletion mutant) in complex with… | electron microscopy | R | — | — |
| 5KHU | Model of human Anaphase-promoting complex/Cyclosome (APC15 deletion mutant), in complex with the… | electron microscopy | R, S | — | 8 (best 0.46) |
| 5KHU | Model of human anaphase-promoting COMPLEX/CYCLOSOME (APC15 deletion mutant), in complex with the… | electron microscopy | R, S | — | — |
| 5LCW | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | Q, R | — | 3 (best 0.84) |
| 5LCW | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | Q, R | — | — |
| 6F0X | Cryo-EM structure of TRIP13 in complex with ATP gamma S, p31comet, C-Mad2 and Cdc20 | electron microscopy | Q | — | 1 (best 0.61) |
| 6F0X | Cryo-EM structure of TRIP13 in complex with ATP gamma S, P31COMET, C- MAD2 and CDC20 | electron microscopy | Q | — | — |
| 6Q6G | Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D1 box class | electron microscopy | R | — | 2 (best 0.82) |
| 6Q6G | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D1 box class | electron microscopy | R | — | — |
| 6Q6H | Cryo-EM structure of the APC/C-Cdc20-Cdk2-cyclinA2-Cks2 complex, the D2 box class | electron microscopy | R | — | 2 (best 0.77) |
| 6Q6H | Cryo-EM structure of the APC/C-CDC20-CDK2-CYCLINA2-CKS2 complex, the D2 box class | electron microscopy | R | — | — |
| 6TLJ | Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic… | electron microscopy | Q, R | — | 2 (best 0.87) |
| 6TLJ | Cryo-EM structure of the anaphase-promoting COMPLEX/CYCLOSOME, in complex with the mitotic… | electron microscopy | Q, R | — | — |
| Q12834 | AlphaFold monomer V2.0 prediction for cell division cycle protein 20 homolog (Q12834) | predicted | A | — | — |
Experiment against prediction
- 4GGD chain B against the predicted model Q12834: TM-score 1.00, RMSD 0.24 Å
- 4GGD chain B against the predicted model Q12834: TM-score 1.00, RMSD 0.24 Å
- 4GGD chain A against the predicted model Q12834: TM-score 1.00, RMSD 0.25 Å
- 4GGD chain A against the predicted model Q12834: TM-score 1.00, RMSD 0.25 Å
- 4N14 chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.54 Å
- 4N14 chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.54 Å
- 4GGA chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.78 Å
- 4GGA chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.78 Å
- 4GGC chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.56 Å
- 4GGC chain A against the predicted model Q12834: TM-score 0.99, RMSD 0.56 Å
Elsewhere
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