UniProt Q05320
Envelope glycoprotein (Q05320)
Envelope glycoprotein (UniProt Q05320): 63 experimental structures on GenesisL1, 21 ligands bound, 259 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q05320
- Protein
- Envelope glycoprotein
- Experimental structures
- 63
- Predicted models
- 0
- Ligands
- 21
- Pockets
- 259 · 26 records with a druggable one
Structures
63 records of Q05320 in the MolNFT archive: 63 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2EBO | Core structure of GP2 from ebola virus | x-ray diffraction | A, B, C | — | — |
| 2EBO | Core structure of GP2 from ebola virus | x-ray diffraction | A, B, C | — | — |
| 2RLJ | NMR Structure of Ebola fusion peptide in SDS micelles at pH 7 | solution nmr | A | — | — |
| 2RLJ | NMR structure of ebola fusion peptide in sds micelles at pH 7 | solution nmr | A | — | — |
| 3CSY | Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing… | x-ray diffraction | I, K, M, O | — | — |
| 3CSY | Crystal structure of the trimeric prefusion ebola virus glycoprotein in complex with a neutralizing… | x-ray diffraction | I, K, M, O | — | — |
| 5FHC | Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion… | x-ray diffraction | J, K | — | 7 (best 0.68) |
| 5FHC | Crystal structure of protective human antibodies 100 and 114 in complex with ebola virus fusion… | x-ray diffraction | J, K | — | — |
| 5HJ3 | Crystal structure of host-primed Ebola virus GP, GPcl. | x-ray diffraction | C, G, K, O | NAG, MAN | — |
| 5HJ3 | Crystal structure of host-primed ebola virus gp, gpcl. | x-ray diffraction | C, G, K, O | — | — |
| 5JQ3 | Crystal structure of Ebola glycoprotein | x-ray diffraction | A, B | NAG, MAN | — |
| 5JQ3 | Crystal structure of ebola glycoprotein | x-ray diffraction | A, B | — | — |
| 5JQ7 | Crystal structure of Ebola glycoprotein in complex with toremifene | x-ray diffraction | A, B | NAG, T0R | 6 (best 0.61) |
| 5JQ7 | Crystal structure of ebola glycoprotein in complex with toremifene | x-ray diffraction | A, B | — | — |
| 5JQB | Crystal structure of Ebola glycoprotein in complex with ibuprofen | x-ray diffraction | A, B | NAG, IBP | 5 (best 0.62) |
| 5JQB | Crystal structure of ebola glycoprotein in complex with ibuprofen | x-ray diffraction | A, B | — | — |
| 5KEL | EBOV GP in complex with variable Fab domains of IgGs c2G4 and c13C6 | electron microscopy | A, B, E, G, F, I | NAG, MAN | 18 (best 0.87) |
| 5KEL | Ebov gp in complex with variable Fab domains of iggs C2G4 and C13C6 | electron microscopy | A, B, E, G, F, I | NAG, MAN | — |
| 5KEM | EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91 | electron microscopy | A, F | — | 14 (best 0.84) |
| 5KEM | Ebov sgp in complex with variable Fab domains of iggs C13C6 and BDBV91 | electron microscopy | A, F | — | — |
| 5KEN | EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6 | electron microscopy | A, B, E, F, K, M | NAG, MAN | 19 (best 0.86) |
| 5KEN | Ebov gp in complex with variable Fab domains of iggs C4G7 and C13C6 | electron microscopy | A, B, E, F, K, M | NAG, MAN | — |
| 6EAY | Structural Basis for Broad Neutralization of Ebolaviruses by an Antibody Targeting the Glycoprotein… | x-ray diffraction | A, B | NAG, MAN | 7 (best 0.66) |
| 6EAY | Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein… | x-ray diffraction | A, B | NAG, MAN | — |
| 6F5U | Crystal structure of ebolavirus glycoprotein in complex with bepridil | x-ray diffraction | A, B | NAG, CQN | 5 (best 0.64) |
| 6F5U | Crystal structure of ebolavirus glycoprotein in complex with bepridil | x-ray diffraction | A, B | NAG, CQN | — |
| 6F6N | Crystal structure of ebolavirus glycoprotein in complex with sertraline | x-ray diffraction | A | NAG, MAN, SRE | 7 (best 0.58) |
| 6F6N | Crystal structure of ebolavirus glycoprotein in complex with sertraline | x-ray diffraction | A | NAG, SRE | — |
| 6F6S | CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH benztropine | x-ray diffraction | A | NAG, CXQ | 6 (best 0.57) |
| 6F6S | Crystal structure of ebolavirus glycoprotein in complex with benztropine | x-ray diffraction | A | NAG, CXQ | — |
| 6G95 | Crystal structure of Ebolavirus glycoprotein in complex with thioridazine | x-ray diffraction | A, B | NAG, RTZ | 5 (best 0.62) |
| 6G95 | Crystal structure of ebolavirus glycoprotein in complex with thioridazine | x-ray diffraction | A, B | NAG, RTZ | — |
| 6G9B | Crystal structure of Ebolavirus glycoprotein in complex with imipramine | x-ray diffraction | A, B | NAG, IXX | 6 (best 0.56) |
| 6G9B | Crystal structure of ebolavirus glycoprotein in complex with imipramine | x-ray diffraction | A, B | NAG, IXX | — |
| 6G9I | Crystal structure of Ebolavirus glycoprotein in complex with clomipramine | x-ray diffraction | A, B | NAG, CXX | 4 (best 0.56) |
| 6G9I | Crystal structure of ebolavirus glycoprotein in complex with clomipramine | x-ray diffraction | A, B | NAG, CXX | — |
| 6HRO | Crystal structure of ebolavirus glycoprotein in complex with inhibitor 118A | x-ray diffraction | A, B | NAG, GKZ | — |
| 6HS4 | Crystal structure of ebolavirus glycoprotein in complex with inhibitor 118 | x-ray diffraction | A, B | NAG, GON | — |
| 6MAM | Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946 | x-ray diffraction | G, H, I, J, K, L | NAG | — |
| 6MAM | Cleaved ebola gp in complex with a broadly neutralizing human antibody, adi-15946 | x-ray diffraction | G, H, I, J, K, L | NAG | — |
| 6NAE | Crystal Structure of Ebola zaire GP protein with bound ARN0074898 | x-ray diffraction | A, B | NAG, MAN, KHG | — |
| 6NAE | Crystal structure of ebola zaire gp protein with bound ARN0074898 | x-ray diffraction | A, B | NAG, MAN, KHG | — |
| 6QD7 | EM structure of a EBOV-GP bound to 3T0331 neutralizing antibody | electron microscopy | A, B, C, E, D, F | NAG, MAN | 20 (best 0.86) |
| 6QD7 | EM structure of a ebov-gp bound to 3T0331 neutralizing antibody | electron microscopy | A, B, C, E, D, F | NAG, MAN | — |
| 6QD8 | EM structure of a EBOV-GP bound to 4M0368 neutralizing antibody | electron microscopy | A, B, C, E, F, D | NAG | 20 (best 0.84) |
| 6QD8 | EM structure of a ebov-gp bound to 4M0368 neutralizing antibody | electron microscopy | A, B, C, E, F, D | NAG | — |
| 7JPH | Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution | x-ray diffraction | B | NAG, PO4 | 6 (best 0.54) |
| 7JPH | Crystal structure of ebov glycoprotein with modified HR1C and HR2 stalk at 3.2 a resolution | x-ray diffraction | B | NAG, PO4 | — |
| 7JPI | Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution | x-ray diffraction | B | NAG, PO4 | 4 (best 0.52) |
| 7JPI | Crystal structure of ebov glycoprotein with modified HR2 stalk at 2.3A resolution | x-ray diffraction | B | NAG, PO4 | — |
| 7LYD | Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075146 | x-ray diffraction | A, B | NAG, MAN, YOD | — |
| 7LYD | Crystal structure of ebola zaire envelope glycoprotein gp in complex with compound ARN0075146 | x-ray diffraction | A, B | NAG, MAN, YOD | — |
| 7LYY | Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075164 | x-ray diffraction | A, B | NAG, YPM | 5 (best 0.59) |
| 7LYY | Crystal structure of ebola zaire envelope glycoprotein gp in complex with compound ARN0075164 | x-ray diffraction | A, B | NAG, YPM | — |
| 7M2D | Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0074953 | x-ray diffraction | A, B | NAG, YPS | 5 (best 0.59) |
| 7M2D | Crystal structure of ebola zaire envelope glycoprotein gp in complex with compound ARN0074953 | x-ray diffraction | A, B | NAG, YPS | — |
| 7SSQ | Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075231 | x-ray diffraction | A, B | NAG, ZQH | 5 (best 0.60) |
| 7SSR | Crystal Structure of Ebola zaire Envelope glycoprotein GP in complex with compound ARN0075093 | x-ray diffraction | A, B | NAG, ZTL | 5 (best 0.59) |
| 7TN9 | Structure of the Inmazeb cocktail and resistance to escape against Ebola virus | electron microscopy | T, S, U, W, V, X | NAG, MAN | 20 (best 0.88) |
| 8DPL | Structure of EBOV GP lacking the mucin-like domain with 2.1.1D5 scFv and 6D6 scFv bound | electron microscopy | I, D, M | NAG, MAN | 16 (best 0.88) |
3 records more on the page itself.
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 49 records
- MAN · alpha-D-mannopyranose · in 20 records
- PO4 · Phosphate ion · in 4 records
- CQN · Bepridil · in 2 records
- CXQ · benztropine · in 2 records
- CXX · 3-(3-chloro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine · in 2 records
- IXX · 3-(5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine · in 2 records
- KHG · (1S,3R,5R,7S)-N-(trans-4-aminocyclohexyl)-3-methyl-5-phenyltricyclo[3.3.1.1~3,7~]decane-1-carboxamide · in 2 records
- RTZ · 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine · in 2 records
- SRE · (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine · in 2 records
- YOD · (1R,3S,5S,7S)-N-[(1r,4R)-4-aminocyclohexyl]-3-[(methylsulfanyl)methyl]-5-phenyladamantane-1-carboxamide · in 2 records
- YPM · (1s,3R,5S,7s)-N-[(1r,4r)-4-aminocyclohexyl]-3,5-diphenyladamantane-1-carboxamide · in 2 records
- YPS · (1R,3S,5R,7R)-N-[(1r,4R)-4-aminocyclohexyl]-3-(ethoxymethyl)-5-phenyladamantane-1-carboxamide · in 2 records
- BMA · beta-D-mannopyranose · in 1 record
- GKZ · 1-[2-[4-[4-(4-chlorophenyl)-3-methyl-1~{H}-pyrazol-5-yl]-3-oxidanyl-phenoxy]ethyl]piperidin-1-ium-4-carboxamide · in 1 record
- GON · 1-[2-[3-oxidanyl-4-(4-phenyl-1~{H}-pyrazol-5-yl) phenoxy]ethyl]piperidine-4-carboxamide · in 1 record
- IBP · Ibuprofen · in 1 record
- T0R · Toremifene · in 1 record
- XJ5 · [(4S)-4-amino-3,3-dimethylpiperidin-1-yl][(1S,3R,5R,7S)-3-methyl-5-phenyladamantan-1-yl]methanone · in 1 record
- ZQH · [(4R)-4-amino-3,3-dimethylpiperidin-1-yl][(1S,3R,5R,6Z,7S)-3-phenyl-6-(2-phenylethylidene)adamantan-1-yl]methanone · in 1 record
- ZTL · (1R,2s,3S,5s,7s)-N-[(1r,4r)-4-(aminomethyl)cyclohexyl]-5-phenyladamantane-2-carboxamide · in 1 record
Elsewhere
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