UniProt Q03347
Runt-related transcription factor 1 (Q03347)
Runt-related transcription factor 1 (UniProt Q03347): 36 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q03347
- Protein
- Runt-related transcription factor 1
- Experimental structures
- 36
- Predicted models
- 1
Structures
37 records of Q03347 in the MolNFT archive: 36 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EAN | THE RUNX1 Runt domain at 1.70A resolution: A structural switch and specifically bound chloride ions… | x-ray diffraction | A | — | — |
| 1EAN | The RUNX1 runt domain at 1.70A resolution: a structural switch and specifically bound chloride ions… | x-ray diffraction | A | — | — |
| 1EAO | THE RUNX1 Runt domain at 1.4A resolution: a structural switch and specifically bound chloride ions… | x-ray diffraction | A, B | — | — |
| 1EAO | The RUNX1 runt domain at 1.4A resolution: a structural switch and specifically bound chloride ions… | x-ray diffraction | A, B | — | — |
| 1EAQ | The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions… | x-ray diffraction | A, B | — | — |
| 1EAQ | The RUNX1 runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions… | x-ray diffraction | A, B | — | — |
| 1HJB | Crystal structure of runx-1/AML1/CBFALPHA runt domain and C/EBPBETA bzip homodimer bound to a DNA… | x-ray diffraction | C, F | — | — |
| 1HJB | Crystal structure of runx-1/AML1/CBFALPHA runt domain and C/EBPBETA bzip homodimer bound to a DNA… | x-ray diffraction | C, F | — | — |
| 1HJC | Crystal structure of runx-1/AML1/CBFALPHA runt domain bound to a DNA fragment from the csf-1R… | x-ray diffraction | A, D | — | — |
| 1HJC | Crystal structure of runx-1/AML1/CBFALPHA runt domain bound to a DNA fragment from the csf-1R… | x-ray diffraction | A, D | — | — |
| 1IO4 | Crystal structure of runx-1/AML1/CBFALPHA runt domain-cbfbeta core domain heterodimer and C/EBPBETA… | x-ray diffraction | C | — | — |
| 1IO4 | Crystal structure of runx-1/AML1/CBFALPHA runt domain- cbfbeta core domain heterodimer and… | x-ray diffraction | C | — | — |
| 2J6W | R164N mutant of the RUNX1 Runt domain | x-ray diffraction | A, B | — | — |
| 2J6W | R164N mutant of the RUNX1 runt domain | x-ray diffraction | A, B | — | — |
| 3WTS | Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer… | x-ray diffraction | A, F | — | — |
| 3WTS | Crystal structure of the complex comprised of ETS1, RUNX1, cbfbeta, and the tcralpha gene enhancer… | x-ray diffraction | A, F | — | — |
| 3WTT | Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha… | x-ray diffraction | A, F | — | — |
| 3WTT | Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, cbfbeta, and the tcralpha… | x-ray diffraction | A, F | — | — |
| 3WTU | Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTU | Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTV | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTV | Crystal structure of the complex comprised of ETS1(V170G), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTW | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTW | Crystal structure of the complex comprised of ETS1(K167A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTX | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTX | Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTY | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WTY | Crystal structure of the complex comprised of ETS1(G333P), RUNX1, cbfbeta, and the tcralpha gene… | x-ray diffraction | A, F | — | — |
| 3WU1 | Crystal structure of the ETS1-RUNX1-DNA ternary complex | x-ray diffraction | A | — | — |
| 3WU1 | Crystal structure of the ETS1-RUNX1-DNA ternary complex | x-ray diffraction | A | — | — |
| 4L0Y | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1) | x-ray diffraction | A | — | — |
| 4L0Y | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 1) | x-ray diffraction | A | — | — |
| 4L0Z | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2) | x-ray diffraction | A | — | — |
| 4L0Z | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 2) | x-ray diffraction | A | — | — |
| 4L18 | Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3) | x-ray diffraction | A, E | — | — |
| 4L18 | Crystal structure of RUNX1 and ETS1 bound to TCR alpha promoter (crystal form 3) | x-ray diffraction | A, E | — | — |
| Q03347 | AlphaFold monomer V2.0 prediction for runt-related transcription factor 1 (Q03347) | predicted | A | — | — |
Experiment against prediction
- 4L0Y chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.36 Å
- 4L0Y chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.36 Å
- 3WU1 chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.36 Å
- 3WU1 chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.36 Å
- 3WTS chain F against the predicted model Q03347: TM-score 0.99, RMSD 0.41 Å
- 3WTS chain F against the predicted model Q03347: TM-score 0.99, RMSD 0.41 Å
- 3WTT chain F against the predicted model Q03347: TM-score 0.99, RMSD 0.41 Å
- 3WTT chain F against the predicted model Q03347: TM-score 0.99, RMSD 0.41 Å
- 1HJC chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.54 Å
- 1HJC chain A against the predicted model Q03347: TM-score 0.99, RMSD 0.54 Å
Elsewhere
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