MolNFT v1 · #10332 · protein + DNA
Crystal structure of runx-1/AML1/CBFALPHA runt domain- cbfbeta core domain heterodimer and C/EBPBETA bzip homodimer bound to a DNA fragment from the csf-1R promoter
1IO4: “Crystal structure of runx-1/AML1/CBFALPHA runt domain- cbfbeta core domain heterodimer and C/EBPBETA bzip…”. X-ray diffraction. MolNFT v1 #10332 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1IO4
- Type
- protein + DNA
- Length
- 433 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P17676, Q03347, Q08024
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | — | dna | 26 | — | — |
| F | — | dna | 26 | — | — |
| A | — | protein | 63 | — | P17676 |
| B | — | protein | 70 | — | P17676 |
| C | — | protein | 120 | — | Q03347 |
| D | — | protein | 128 | — | Q08024 |
Compared structures
- 1IO4 · Crystal structure of runx-1/AML1/CBFALPHA runt domain-cbfbeta core domain heterodimer and… · the same entry in another collection · chain D against D, TM-score 1.00
- Q03347 · AlphaFold monomer V2.0 prediction for runt-related transcription factor 1 (Q03347) · a predicted model of the same protein · chain C against A, TM-score 0.98
- Q08024 · AlphaFold monomer V2.0 prediction for core-binding factor subunit beta (Q08024) · a predicted model of the same protein · chain D against A, TM-score 0.95
- P17676 · AlphaFold monomer V2.0 prediction for CCAAT/ENHANCER-binding protein beta (P17676) · a predicted model of the same protein · chain B against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17676
- Every structure of UniProt Q03347
- Every structure of UniProt Q08024
- Elsewhere: RCSB PDB 1IO4 · PDBe 1IO4 · UniProt P17676 · UniProt Q03347 · UniProt Q08024
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