UniProt Q02821
Importin subunit alpha (Q02821)
Importin subunit alpha (UniProt Q02821): 20 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q02821
- Protein
- Importin subunit alpha
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
21 records of Q02821 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BK5 | Karyopherin alpha from saccharomyces cerevisiae | x-ray diffraction | A, B | — | — |
| 1BK5 | Karyopherin alpha from saccharomyces cerevisiae | x-ray diffraction | A, B | — | — |
| 1BK6 | Karyopherin alpha (yeast) + SV40 T antigen nls | x-ray diffraction | A, B | — | — |
| 1BK6 | Karyopherin alpha (yeast) + SV40 T antigen nls | x-ray diffraction | A, B | — | — |
| 1EE4 | Crystal structure of yeast karyopherin (importin) alpha in a complex with a C-myc nls peptide | x-ray diffraction | A, B | — | — |
| 1EE4 | Crystal structure of yeast karyopherin (importin) alpha in a complex with a C-myc nls peptide | x-ray diffraction | A, B | — | — |
| 1EE5 | Yeast karyopherin (importin) alpha in a complex with a nucleoplasmin nls peptide | x-ray diffraction | A | — | — |
| 1EE5 | Yeast karyopherin (importin) alpha in a complex with a nucleoplasmin nls peptide | x-ray diffraction | A | — | — |
| 1UN0 | Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment | x-ray diffraction | A, B | — | — |
| 1UN0 | Crystal structure of yeast karyopherin (importin) alpha in complex with a NUP2P N-terminal fragment | x-ray diffraction | A, B | — | — |
| 2C1T | Structure of the Kap60p:Nup2 complex | x-ray diffraction | A, B | — | — |
| 2C1T | Structure of the KAP60P:NUP2 complex | x-ray diffraction | A, B | — | — |
| 4PVZ | Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of… | x-ray diffraction | A, B | — | — |
| 4PVZ | Structure of yeast importin a bound to the membrane protein nuclear localization signal sequence of… | x-ray diffraction | A, B | — | — |
| 4XZR | Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of… | x-ray diffraction | B | — | 3 (best 0.40) |
| 4XZR | Structure of yeast importin a bound to the membrane protein nuclear localization signal sequence of… | x-ray diffraction | B | — | — |
| 5H2W | Crystal structure of the karyopherin KAP60P bound to the sumo protease ULP1P (150-340) | x-ray diffraction | A, C | — | — |
| 5H2X | Crystal structure of the karyopherin Kap60p bound to the SUMO protease Ulp1p (150-172) | x-ray diffraction | A | — | — |
| 5H2X | Crystal structure of the karyopherin KAP60P bound to the sumo protease ULP1P (150-172) | x-ray diffraction | A | — | — |
| 5T94 | Crystal structure of KAP60 bound to yeast RCC1 (PRP20) | x-ray diffraction | B | — | — |
| Q02821 | AlphaFold monomer V2.0 prediction for importin subunit alpha (Q02821) | predicted | A | — | — |
Experiment against prediction
- 5H2X chain A against the predicted model Q02821: TM-score 0.99, RMSD 0.69 Å
- 5H2X chain A against the predicted model Q02821: TM-score 0.99, RMSD 0.69 Å
- 4XZR chain B against the predicted model Q02821: TM-score 0.99, RMSD 0.88 Å
- 4XZR chain B against the predicted model Q02821: TM-score 0.99, RMSD 0.88 Å
- 5H2W chain C against the predicted model Q02821: TM-score 0.99, RMSD 0.86 Å
- 1BK6 chain A against the predicted model Q02821: TM-score 0.99, RMSD 0.87 Å
- 1BK6 chain A against the predicted model Q02821: TM-score 0.99, RMSD 0.87 Å
- 5H2W chain A against the predicted model Q02821: TM-score 0.99, RMSD 0.90 Å
- 1BK5 chain A against the predicted model Q02821: TM-score 0.98, RMSD 0.95 Å
- 1BK5 chain A against the predicted model Q02821: TM-score 0.98, RMSD 0.95 Å
Elsewhere
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