UniProt P56689
DNA polymerase (P56689)
DNA polymerase (UniProt P56689), EC 2.7.7.7: 20 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 28 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P56689
- Protein
- DNA polymerase
- EC
- 2.7.7.7
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 28 · 3 records with a druggable one
Structures
21 records of P56689 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1TGO | Thermostable B type DNA polymerase from thermococcus gorgonarius | x-ray diffraction | A | — | — |
| 1TGO | Thermostable B type DNA polymerase from thermococcus gorgonarius | x-ray diffraction | A | — | — |
| 2VWJ | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. | x-ray diffraction | A | — | — |
| 2VWJ | Uracil recognition in archaeal DNA polymerases captured by X-ray crystallography. | x-ray diffraction | A | — | — |
| 2VWK | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase… | x-ray diffraction | A | — | — |
| 2VWK | Uracil recognition in archaeal DNA polymerases captured by X-ray crystallography. V93Q polymerase… | x-ray diffraction | A | — | — |
| 2XHB | Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with… | x-ray diffraction | A | — | — |
| 2XHB | Crystal structure of DNA polymerase from thermococcus gorgonarius in complex with… | x-ray diffraction | A | — | — |
| 7B06 | TgoT_RT521 apo | x-ray diffraction | A | — | — |
| 7B06 | TGOT_RT521 apo | x-ray diffraction | A | — | — |
| 7B07 | TgoT_6G12 apo | x-ray diffraction | A | CA | 9 (best 0.65) |
| 7B07 | TGOT_6G12 apo | x-ray diffraction | A | CA | — |
| 7B08 | TgoT apo | x-ray diffraction | A | TTP | 10 (best 0.64) |
| 7B08 | TGOT APO | x-ray diffraction | A | TTP | — |
| 7B0F | TGOT_6G12 binary complex | x-ray diffraction | A | TTP | — |
| 7B0G | TgoT_6G12 binary with 2 hCTPs | x-ray diffraction | A | CTP | — |
| 7B0G | TGOT_6G12 binary with 2 hctps | x-ray diffraction | A | CTP | — |
| 7B0H | TgoT_6G12 Ternary complex | x-ray diffraction | E, F | MN, MG, TTP | — |
| 7B0H | TGOT_6G12 ternary complex | x-ray diffraction | E, F | MN, MG, TTP | — |
| 9GP8 | Crystal Structure of TgoT_PGLVVWA XNA Polymerase (Apo) | x-ray diffraction | A | SO4 | 9 (best 0.75) |
| P56689 | AlphaFold monomer V2.0 prediction for DNA polymerase (P56689) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7B06 chain A against the predicted model P56689: TM-score 0.95, RMSD 2.44 Å
- 7B06 chain A against the predicted model P56689: TM-score 0.95, RMSD 2.44 Å
- 7B0F chain A against the predicted model P56689: TM-score 0.95, RMSD 2.35 Å
- 7B0H chain E against the predicted model P56689: TM-score 0.92, RMSD 3.08 Å
- 7B0H chain E against the predicted model P56689: TM-score 0.92, RMSD 3.08 Å
- 9GP8 chain A against the predicted model P56689: TM-score 0.92, RMSD 2.99 Å
- 7B0G chain A against the predicted model P56689: TM-score 0.92, RMSD 3.03 Å
- 7B0G chain A against the predicted model P56689: TM-score 0.92, RMSD 3.03 Å
- 7B0H chain F against the predicted model P56689: TM-score 0.91, RMSD 3.39 Å
- 7B0H chain F against the predicted model P56689: TM-score 0.91, RMSD 3.39 Å
Elsewhere
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