MolNFT v1 · #173446 · protein
TGOT_RT521 apo
7B06 · DNA polymerase: “TGOT_RT521 apo”. X-ray diffraction, 8 pockets (best druggability 0.62). MolNFT v1 #173446 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7B06
- Type
- protein
- Length
- 685 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA polymerase
- EC
- 2.7.7.7
- UniProt
- P56689
- Pockets
- 8 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase (EC 2.7.7.7) | protein | 685 | 43% helix, 22% strand | P56689 |
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 265 | 0.62 | 0.80 | 32 | empty |
| 2 | 439 | 0.60 | 0.75 | 55 | empty |
| 3 | 229 | 0.56 | 0.78 | 28 | empty |
| 4 | 111 | 0.47 | 0.79 | 15 | empty |
| 5 | 87 | 0.39 | 0.77 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P56689
- Elsewhere: RCSB PDB 7B06 · PDBe 7B06 · UniProt P56689
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