UniProt P54818
Galactocerebrosidase (P54818)
Galactocerebrosidase (UniProt P54818), EC 3.2.1.46: 27 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P54818
- Protein
- Galactocerebrosidase
- EC
- 3.2.1.46
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 3 · 0 records with a druggable one
Structures
28 records of P54818 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ZR5 | Structure of galactocerebrosidase from mouse | x-ray diffraction | A | — | — |
| 3ZR5 | Structure of galactocerebrosidase from mouse | x-ray diffraction | A | — | — |
| 3ZR6 | Structure of galactocerebrosidase from mouse in complex with galactose | x-ray diffraction | A | — | — |
| 3ZR6 | Structure of galactocerebrosidase from mouse in complex with galactose | x-ray diffraction | A | — | — |
| 4CCC | Structure of mouse galactocerebrosidase with 4NBDG: enzyme-substrate complex | x-ray diffraction | A | — | — |
| 4CCC | Structure of mouse galactocerebrosidase with 4NBDG: enzyme-substrate complex | x-ray diffraction | A | — | — |
| 4CCD | Structure of mouse galactocerebrosidase with D-galactal: enzyme- intermediate complex | x-ray diffraction | A | — | — |
| 4CCD | Structure of mouse galactocerebrosidase with D-galactal: enzyme- intermediate complex | x-ray diffraction | A | — | — |
| 4CCE | Structure of mouse galactocerebrosidase with galactose: enzyme- product complex | x-ray diffraction | A | — | — |
| 4CCE | Structure of mouse galactocerebrosidase with galactose: enzyme- product complex | x-ray diffraction | A | — | — |
| 4UFH | Mouse Galactocerebrosidase complexed with iso-galacto-fagomine IGF | x-ray diffraction | A | — | — |
| 4UFH | Mouse galactocerebrosidase complexed with iso-galacto-fagomine igf | x-ray diffraction | A | — | — |
| 4UFI | Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF | x-ray diffraction | A | — | — |
| 4UFI | Mouse galactocerebrosidase complexed with aza-galacto-fagomine agf | x-ray diffraction | A | — | — |
| 4UFJ | Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL | x-ray diffraction | A | — | — |
| 4UFJ | Mouse galactocerebrosidase complexed with iso-galacto-fagomine lactam igl | x-ray diffraction | A | — | — |
| 4UFK | Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL | x-ray diffraction | A | — | — |
| 4UFK | Mouse galactocerebrosidase complexed with dideoxy-imino-lyxitol dil | x-ray diffraction | A | — | — |
| 4UFL | Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN | x-ray diffraction | A | — | — |
| 4UFL | Mouse galactocerebrosidase complexed with deoxy-galacto-noeurostegine dgn | x-ray diffraction | A | — | — |
| 4UFM | Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ | x-ray diffraction | A | — | — |
| 4UFM | Mouse galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin dgj | x-ray diffraction | A | — | — |
| 5NXB | Mouse galactocerebrosidase in complex with saposin A | x-ray diffraction | A, B | NAG, CA | — |
| 5NXB | Mouse galactocerebrosidase in complex with saposin a | x-ray diffraction | A, B | NAG, CA | — |
| 6Y6S | Mouse Galactocerebrosidase complexed with galacto-noeurostegine GNS at pH 6.8 | x-ray diffraction | A | NAG, ODW, CA, NI | 3 (best 0.47) |
| 6Y6S | Mouse galactocerebrosidase complexed with galacto-noeurostegine gns at pH 6.8 | x-ray diffraction | A | NAG, ODW, CA, NI | — |
| 6Y6T | Mouse galactocerebrosidase complexed with galacto-noeurostegine gns at pH 4.6 | x-ray diffraction | A | NAG, ODW, CA, NI | — |
| P54818 | AlphaFold monomer V2.0 prediction for galactocerebrosidase (P54818) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4CCE chain A against the predicted model P54818: TM-score 1.00, RMSD 0.21 Å
- 4CCE chain A against the predicted model P54818: TM-score 1.00, RMSD 0.21 Å
- 4CCD chain A against the predicted model P54818: TM-score 1.00, RMSD 0.21 Å
- 4CCD chain A against the predicted model P54818: TM-score 1.00, RMSD 0.21 Å
- 4UFJ chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
- 4UFJ chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
- 6Y6S chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
- 6Y6S chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
- 4UFK chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
- 4UFK chain A against the predicted model P54818: TM-score 1.00, RMSD 0.22 Å
Elsewhere
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