UniProt P53611
Geranylgeranyl transferase type-2 subunit beta (P53611)
Geranylgeranyl transferase type-2 subunit beta (UniProt P53611), EC 2.5.1.60: 10 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 78 pockets. Binding sites, druggability and experiment against…
- UniProt
- P53611
- Protein
- Geranylgeranyl transferase type-2 subunit beta
- EC
- 2.5.1.60
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 78 · 11 records with a druggable one
Structures
11 records of P53611 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J6X | Crystal structure of apo GGTaseIII | x-ray diffraction | B | MG | 7 (best 0.79) |
| 6J6X | Crystal structure of apo ggtaseiii | x-ray diffraction | B | MG | 7 (best 0.79) |
| 6J74 | Complex of GGTaseIII and full-length Ykt6 | x-ray diffraction | B | PO4, ZN | 7 (best 0.84) |
| 6J74 | Complex of ggtaseiii and full-length YKT6 | x-ray diffraction | B | PO4, ZN | 7 (best 0.84) |
| 6J7F | Complex of GGTaseIII, farnesyl-Ykt6 (C-terminal methylated), and GGPP | x-ray diffraction | B | FAR, GER, DPO | 8 (best 0.87) |
| 6J7F | Complex of ggtaseiii, farnesyl-YKT6 (C-terminal methylated), and ggpp | x-ray diffraction | B | FAR, GER, DPO | 8 (best 0.87) |
| 6J7X | Complex of GGTaseIII, farnesyl-Ykt6, and GGPP | x-ray diffraction | B | GRG | 6 (best 0.81) |
| 6J7X | Complex of ggtaseiii, farnesyl-YKT6, and ggpp | x-ray diffraction | B | GRG | 6 (best 0.81) |
| 6O60 | Crystal structure of GGTase3-FBXL2-SKP1 complex | x-ray diffraction | B | ZN | 10 (best 0.82) |
| 6O60 | Crystal structure of GGTASE3-FBXL2-SKP1 complex | x-ray diffraction | B | ZN | 10 (best 0.82) |
| P53611 | AlphaFold monomer V2.0 prediction for geranylgeranyl transferase type-2 subunit beta (P53611) | predicted | A | — | 2 (best 0.69) |
Ligands
Experiment against prediction
- 6J7X chain B against the predicted model P53611: TM-score 0.99, RMSD 0.72 Å
- 6J7X chain B against the predicted model P53611: TM-score 0.99, RMSD 0.72 Å
- 6J74 chain B against the predicted model P53611: TM-score 0.99, RMSD 0.74 Å
- 6J74 chain B against the predicted model P53611: TM-score 0.99, RMSD 0.74 Å
- 6J7F chain B against the predicted model P53611: TM-score 0.99, RMSD 0.84 Å
- 6J7F chain B against the predicted model P53611: TM-score 0.99, RMSD 0.84 Å
- 6O60 chain B against the predicted model P53611: TM-score 0.98, RMSD 1.06 Å
- 6O60 chain B against the predicted model P53611: TM-score 0.98, RMSD 1.06 Å
- 6J6X chain B against the predicted model P53611: TM-score 0.97, RMSD 1.36 Å
- 6J6X chain B against the predicted model P53611: TM-score 0.97, RMSD 1.36 Å
Elsewhere
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