UniProt P42641
GTPase ObgE/CgtA (P42641)
GTPase ObgE/CgtA (UniProt P42641), EC 3.6.5.-: 13 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P42641
- Protein
- GTPase ObgE/CgtA
- EC
- 3.6.5.-
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 6 records with a druggable one
Structures
14 records of P42641 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | electron microscopy | 9 | — | — |
| 4CSU | Cryo-EM structures of the 50S ribosome subunit bound with obge | electron microscopy | 9 | — | — |
| 5M04 | Structure of ObgE from Escherichia coli | x-ray diffraction | A | GDP, MG | — |
| 5M04 | Structure of obge from escherichia COLI | x-ray diffraction | A | GDP, MG | — |
| 7BL2 | pre-50S-ObgE particle state 1 | electron microscopy | 9P1 | — | 2 (best 0.86) |
| 7BL3 | pre-50S-ObgE particle state 2 | electron microscopy | 9P | — | — |
| 7BL4 | in vitro reconstituted 50S-ObgE-GMPPNP-RsfS particle | electron microscopy | 9 | MG, GNP | 2 (best 0.87) |
| 7BL4 | In vitro reconstituted 50S-obge-gmppnp-rsfs particle | electron microscopy | 9 | MG, GNP | — |
| 7BL5 | pre-50S-ObgE particle | electron microscopy | 9 | GDP, MG | 1 (best 0.87) |
| 7BL5 | Pre-50S-obge particle | electron microscopy | 9 | GDP, MG | — |
| 7BL6 | 50S-ObgE-GMPPNP particle | electron microscopy | 9 | MG, GNP | 1 (best 0.82) |
| 7BL6 | 50S-obge-gmppnp particle | electron microscopy | 9 | MG, GNP | — |
| 8BFT | The E. coli TrpD2 protein YbiB in complex with a C-terminal peptide from ObgE | x-ray diffraction | B | — | 1 (best 0.65) |
| P42641 | AlphaFold monomer V2.0 prediction for GTPase OBGE/CGTA (P42641) | predicted | A | — | 4 (best 0.65) |
Ligands
Experiment against prediction
- 5M04 chain A against the predicted model P42641: TM-score 0.95, RMSD 1.66 Å
- 5M04 chain A against the predicted model P42641: TM-score 0.95, RMSD 1.66 Å
- 8BFT chain B against the predicted model P42641: TM-score 0.67, RMSD 0.87 Å
- 7BL4 chain 9 against the predicted model P42641: TM-score 0.58, RMSD 5.30 Å
- 7BL4 chain 9 against the predicted model P42641: TM-score 0.58, RMSD 5.30 Å
- 7BL6 chain 9 against the predicted model P42641: TM-score 0.58, RMSD 5.35 Å
- 7BL6 chain 9 against the predicted model P42641: TM-score 0.58, RMSD 5.35 Å
- 7BL5 chain 9 against the predicted model P42641: TM-score 0.53, RMSD 4.80 Å
- 7BL5 chain 9 against the predicted model P42641: TM-score 0.53, RMSD 4.80 Å
- 7BL3 chain 9P against the predicted model P42641: TM-score 0.53, RMSD 4.98 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.