MolNFT v1 · #279407 · protein
AlphaFold monomer V2.0 prediction for GTPase OBGE/CGTA (P42641)
P42641: “AlphaFold monomer V2.0 prediction for GTPase OBGE/CGTA (P42641)”. 4 pockets (best druggability 0.65). MolNFT v1 #279407 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P42641
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4646f197d9d8E25cddf613E3d4a2609797139977
- Molecule
- GTPase OBGE/CGTA
- UniProt
- P42641
- Pockets
- 4 · best druggability 0.65
Structure
1 distinct chain · 24% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GTPase OBGE/CGTA | protein | 390 | 24% helix, 24% strand | P42641 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.65 | 0.81 | 42 | empty |
| 2 | 303 | 0.61 | 0.79 | 34 | empty |
| 3 | 58 | 0.42 | 0.82 | 18 | empty |
| 4 | 60 | 0.34 | 0.77 | 16 | empty |
Compared structures
- 5M04 · Structure of obge from escherichia COLI · an experimental structure of the same protein · chain A against A, TM-score 0.82
- 5M04 · Structure of ObgE from Escherichia coli · an experimental structure of the same protein · chain A against A, TM-score 0.82
- 7BL4 · In vitro reconstituted 50S-obge-gmppnp-rsfs particle · an experimental structure of the same protein · chain A against 9, TM-score 0.51
- 7BL6 · 50S-obge-gmppnp particle · an experimental structure of the same protein · chain A against 9, TM-score 0.51
- 7BL5 · pre-50S-ObgE particle · an experimental structure of the same protein · chain A against 9, TM-score 0.47
- 7BL5 · Pre-50S-obge particle · an experimental structure of the same protein · chain A against 9, TM-score 0.47
- 7BL3 · pre-50S-ObgE particle state 2 · an experimental structure of the same protein · chain A against 9P, TM-score 0.47
- 7BL2 · pre-50S-ObgE particle state 1 · an experimental structure of the same protein · chain A against 9P1, TM-score 0.47
- 4CSU · Cryo-EM structures of the 50S ribosome subunit bound with ObgE · an experimental structure of the same protein · chain A against 9, TM-score 0.46
- 4CSU · Cryo-EM structures of the 50S ribosome subunit bound with obge · an experimental structure of the same protein · chain A against 9, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42641
- Elsewhere: UniProt P42641 · AlphaFold DB P42641
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