GL1X · GenesisL1 explorer

MolNFT v1 · #279407 · protein

AlphaFold monomer V2.0 prediction for GTPase OBGE/CGTA (P42641)

P42641: “AlphaFold monomer V2.0 prediction for GTPase OBGE/CGTA (P42641)”. 4 pockets (best druggability 0.65). MolNFT v1 #279407 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P42641
Type
protein
Length
390 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4646f197d9d8E25cddf613E3d4a2609797139977
Molecule
GTPase OBGE/CGTA
UniProt
P42641
Pockets
4 · best druggability 0.65

Structure

1 distinct chain · 24% helix, 24% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGTPase OBGE/CGTAprotein39024% helix, 24% strandP42641

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13050.650.8142empty
23030.610.7934empty
3580.420.8218empty
4600.340.7716empty

Compared structures

  • 5M04 · Structure of obge from escherichia COLI · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 5M04 · Structure of ObgE from Escherichia coli · an experimental structure of the same protein · chain A against A, TM-score 0.82
  • 7BL4 · In vitro reconstituted 50S-obge-gmppnp-rsfs particle · an experimental structure of the same protein · chain A against 9, TM-score 0.51
  • 7BL6 · 50S-obge-gmppnp particle · an experimental structure of the same protein · chain A against 9, TM-score 0.51
  • 7BL5 · pre-50S-ObgE particle · an experimental structure of the same protein · chain A against 9, TM-score 0.47
  • 7BL5 · Pre-50S-obge particle · an experimental structure of the same protein · chain A against 9, TM-score 0.47
  • 7BL3 · pre-50S-ObgE particle state 2 · an experimental structure of the same protein · chain A against 9P, TM-score 0.47
  • 7BL2 · pre-50S-ObgE particle state 1 · an experimental structure of the same protein · chain A against 9P1, TM-score 0.47
  • 4CSU · Cryo-EM structures of the 50S ribosome subunit bound with ObgE · an experimental structure of the same protein · chain A against 9, TM-score 0.46
  • 4CSU · Cryo-EM structures of the 50S ribosome subunit bound with obge · an experimental structure of the same protein · chain A against 9, TM-score 0.46

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