UniProt P41805
60S ribosomal protein L10 (P41805)
60S ribosomal protein L10 (UniProt P41805): 65 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P41805
- Protein
- 60S ribosomal protein L10
- Experimental structures
- 65
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 5 · 4 records with a druggable one
Structures
66 records of P41805 in the MolNFT archive: 65 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J6X | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | electron microscopy | 50 | — | — |
| 3J6Y | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | electron microscopy | 50 | — | — |
| 3J77 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 60 | — | — |
| 3J78 | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class… | electron microscopy | 60 | — | — |
| 4U3M | Crystal structure of Anisomycin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U3N | Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U3U | Crystal structure of Cycloheximide bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4N | Crystal structure of Edeine bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4O | Crystal structure of Geneticin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4Q | Crystal structure of Homoharringtonine bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4R | Crystal structure of Lactimidomycin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4U | Crystal structure of Lycorine bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4Y | Crystal structure of Pactamycin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U4Z | Crystal structure of Phyllanthoside bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U50 | Crystal structure of Verrucarin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U51 | Crystal structure of Narciclasine bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U52 | Crystal structure of Nagilactone C bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U53 | Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U55 | Crystal structure of Cryptopleurine bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U56 | Crystal structure of Blasticidin S bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4U6F | Crystal structure of T-2 toxin bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | — | — |
| 4V4B | Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models… | electron microscopy | BI | — | — |
| 4V6I | Localization of the small subunit ribosomal proteins into a 6.1 A cryo-EM map of Saccharomyces… | electron microscopy | BI | — | — |
| 4V7R | Yeast 80S ribosome. | x-ray diffraction | BJ, DJ | — | — |
| 4V88 | The structure of the eukaryotic ribosome at 3.0 A resolution. | x-ray diffraction | BI, DI | — | — |
| 4V8T | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | electron microscopy | I | — | — |
| 4V8Y | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BI | — | — |
| 4V8Z | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | electron microscopy | BI | — | — |
| 4ZOX | Crystal structure of the Saccharomyces cerevisiae Sqt1 bound to the N-terminus of the ribosomal… | x-ray diffraction | B | — | — |
| 4ZOX | Crystal structure of the saccharomyces cerevisiae SQT1 bound to the N- terminus of the ribosomal… | x-ray diffraction | B | — | — |
| 5GAK | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | electron microscopy | s | — | — |
| 5JUP | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | N | — | — |
| 5JUS | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | N | — | — |
| 5JUU | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura… | electron microscopy | N | — | — |
| 5M1J | Nonstop ribosomal complex bound with Dom34 and Hbs1 | electron microscopy | I5 | MG | — |
| 5MC6 | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | electron microscopy | BD | — | — |
| 5MEI | Crystal structure of Agelastatin A bound to the 80S ribosome | x-ray diffraction | r, CL | OHX, MG | — |
| 5NDG | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | x-ray diffraction | M0, m0 | MG | 1 (best 0.88) |
| 5T6R | Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome… | electron microscopy | L | — | — |
| 6GQ1 | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin) | electron microscopy | I | — | — |
| 6GQB | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | electron microscopy | I | — | — |
| 6GQV | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | electron microscopy | I | — | — |
| 6HD7 | Cryo-EM structure of the ribosome-NatA complex | electron microscopy | s | — | — |
| 6HHQ | Crystal structure of compound C45 bound to the yeast 80S ribosome | x-ray diffraction | r, CL | OHX, MG | — |
| 6I7O | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways… | electron microscopy | BD, YD | — | — |
| 6N8O | Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit | electron microscopy | Z | — | — |
| 6Q8Y | Cryo-EM structure of the mRNA translating and degrading yeast 80S ribosome-Xrn1 nuclease complex | electron microscopy | BD | — | — |
| 6RI5 | Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles | electron microscopy | q | — | — |
| 6T7I | Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination. | electron microscopy | LI | — | — |
| 6T83 | Structure of yeast disome (di-ribosome) stalled on poly(A) tract. | electron microscopy | Iy, La | — | — |
| 6TNU | Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. | electron microscopy | BD | — | — |
| 6WOO | CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP | electron microscopy | I | MET | — |
| 6Z6J | Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition | electron microscopy | LI | — | — |
| 7MPI | Stm1 bound vacant 80S structure isolated from cbf5-D95A | electron microscopy | AI | MG | — |
| 7MPJ | Stm1 bound vacant 80S structure isolated from wild-type | electron microscopy | AI | MG | — |
| 7NRC | Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA… | electron microscopy | LL | — | 1 (best 0.86) |
| 7NRD | Structure of the yeast Gcn1 bound to a colliding stalled 80S ribosome with MBF1, A/P-tRNA and… | electron microscopy | LL | — | — |
| 7ZS5 | Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA | electron microscopy | BK | — | — |
| 7ZW0 | FAP-80S Complex - Rotated state | electron microscopy | LM | — | — |
| 8BIP | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | electron microscopy | LI | MG | — |
6 records more on the page itself.
Ligands
Experiment against prediction
- 7MPJ chain AI against the predicted model P41805: TM-score 0.98, RMSD 0.69 Å
- 8CIV chain MM against the predicted model P41805: TM-score 0.98, RMSD 0.74 Å
- 7ZW0 chain LM against the predicted model P41805: TM-score 0.98, RMSD 0.76 Å
- 5NDG chain M0 against the predicted model P41805: TM-score 0.98, RMSD 0.76 Å
- 7MPI chain AI against the predicted model P41805: TM-score 0.98, RMSD 0.77 Å
- 8CG8 chain MM against the predicted model P41805: TM-score 0.98, RMSD 0.81 Å
- 8P8U chain LN against the predicted model P41805: TM-score 0.98, RMSD 0.82 Å
- 8P8N chain LN against the predicted model P41805: TM-score 0.98, RMSD 0.82 Å
- 6T7I chain LI against the predicted model P41805: TM-score 0.98, RMSD 0.88 Å
- 8BIP chain LI against the predicted model P41805: TM-score 0.98, RMSD 0.89 Å
Elsewhere
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