MolNFT v1 · #112560 · protein
Crystal structure of the saccharomyces cerevisiae SQT1 bound to the N- terminus of the ribosomal protein L10
4ZOX · Ribosome assembly protein SQT1: “Crystal structure of the saccharomyces cerevisiae SQT1 bound to the N- terminus of the ribosomal protein L10”. X-ray diffraction, 2 pockets (best druggability 0.76). MolNFT v1 #112560 on GenesisL1…
- PDB
- 4ZOX
- Type
- protein
- Length
- 393 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ribosome assembly protein SQT1; 60S ribosomal protein L10
- UniProt
- P35184, P41805
- Pockets
- 2 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ribosome assembly protein SQT1 | protein | 379 | 3% helix, 52% strand | P35184 |
| B | 60S ribosomal protein L10 | protein | 14 | 43% helix, 0% strand | P41805 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 946 | 0.76 | 0.79 | 66 | empty |
| 2 | 76 | 0.31 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 785 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 4ZOX · Crystal structure of the Saccharomyces cerevisiae Sqt1 bound to the N-terminus of the… · the same entry in another collection · chain A against A, TM-score 1.00
- P35184 · AlphaFold monomer V2.0 prediction for ribosome assembly protein SQT1 (P35184) · a predicted model of the same protein · chain A against A, TM-score 1.00
- P41805 · AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P41805) · a predicted model of the same protein · chain B against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35184
- Every structure of UniProt P41805
- Elsewhere: RCSB PDB 4ZOX · PDBe 4ZOX · UniProt P35184 · UniProt P41805
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