MolNFT v1 · #349219 · protein
AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P41805)
P41805: “AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P41805)”. 2 pockets (best druggability 0.51). MolNFT v1 #349219 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P41805
- Type
- protein
- Length
- 221 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x024E776336F8eD4B2eC1b7523E5a42EABB50f840
- Molecule
- 60S ribosomal protein L10
- UniProt
- P41805
- Pockets
- 2 · best druggability 0.51
Structure
1 distinct chain · 30% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 60S ribosomal protein L10 | protein | 221 | 30% helix, 25% strand | P41805 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.51 | 0.84 | 20 | empty |
| 2 | 72 | 0.37 | 0.78 | 20 | empty |
Compared structures
- 5MC6 · Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae · an experimental structure of the same protein · chain A against BD, TM-score 0.96
- 6TNU · Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. · an experimental structure of the same protein · chain A against BD, TM-score 0.96
- 6T83 · Structure of yeast disome (di-ribosome) stalled on poly(A) tract. · an experimental structure of the same protein · chain A against Iy, TM-score 0.96
- 7NRC · Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A… · an experimental structure of the same protein · chain A against LL, TM-score 0.95
- 5GAK · Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A · an experimental structure of the same protein · chain A against s, TM-score 0.95
- 7ZS5 · Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA · an experimental structure of the same protein · chain A against BK, TM-score 0.95
- 4U52 · Crystal structure of Nagilactone C bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
- 4U4Z · Crystal structure of Phyllanthoside bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
- 4U4R · Crystal structure of Lactimidomycin bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
- 4U3U · Crystal structure of Cycloheximide bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
- 4U6F · Crystal structure of T-2 toxin bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
- 4U3M · Crystal structure of Anisomycin bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P41805
- Elsewhere: UniProt P41805 · AlphaFold DB P41805
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