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AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P41805)

Analyse AlphaFold monomer V2.0 prediction for 60S ribosomal protein L10 (P41805) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P41805
Type
protein
Length
221 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x024E776336F8eD4B2eC1b7523E5a42EABB50f840
Molecule
60S ribosomal protein L10
UniProt
P41805
Pockets
2 · best druggability 0.51

Structure

1 distinct chain · 30% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A60S ribosomal protein L10protein22130% helix, 25% strandP41805

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1760.510.8420empty
2720.370.7820empty

Compared structures

  • 5MC6 · Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae · an experimental structure of the same protein · chain A against BD, TM-score 0.96
  • 6TNU · Yeast 80S ribosome in complex with eIF5A and decoding A-site and P-site tRNAs. · an experimental structure of the same protein · chain A against BD, TM-score 0.96
  • 8CIV · Translocation intermediate 5 (TI-5) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against MM, TM-score 0.96
  • 6T83 · Structure of yeast disome (di-ribosome) stalled on poly(A) tract. · an experimental structure of the same protein · chain A against Iy, TM-score 0.96
  • 8CG8 · Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2… · an experimental structure of the same protein · chain A against MM, TM-score 0.95
  • 7NRC · Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A… · an experimental structure of the same protein · chain A against LL, TM-score 0.95
  • 5GAK · Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A · an experimental structure of the same protein · chain A against s, TM-score 0.95
  • 7ZS5 · Structure of 60S ribosomal subunit from S. cerevisiae with eIF6 and tRNA · an experimental structure of the same protein · chain A against BK, TM-score 0.95
  • 4U52 · Crystal structure of Nagilactone C bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
  • 4U4Z · Crystal structure of Phyllanthoside bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
  • 4U4R · Crystal structure of Lactimidomycin bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94
  • 4U3U · Crystal structure of Cycloheximide bound to the yeast 80S ribosome · an experimental structure of the same protein · chain A against m0, TM-score 0.94

Analyse

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