UniProt P35523
Chloride channel protein 1 (P35523)
Chloride channel protein 1 (UniProt P35523): 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 72 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35523
- Protein
- Chloride channel protein 1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 72 · 4 records with a druggable one
Structures
12 records of P35523 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6COY | Human clc-1 chloride ion channel, transmembrane domain | electron microscopy | A, B | CL | — |
| 6COZ | Human clc-1 chloride ion channel, C-terminal cytosolic domain | electron microscopy | A, B | — | — |
| 6QV6 | Cryoem structure of the human clc-1 chloride channel, membrane domain | electron microscopy | B, A | — | — |
| 6QVB | Cryoem structure of the human clc-1 chloride channel, cbs state 3 | electron microscopy | B, A | — | — |
| 6QVC | CryoEM structure of the human ClC-1 chloride channel, CBS state 1 | electron microscopy | B, A | — | 20 (best 0.81) |
| 6QVC | Cryoem structure of the human clc-1 chloride channel, cbs state 1 | electron microscopy | B, A | — | — |
| 6QVD | CryoEM structure of the human ClC-1 chloride channel, CBS state 2 | electron microscopy | B, A | — | 20 (best 0.88) |
| 6QVD | Cryoem structure of the human clc-1 chloride channel, cbs state 2 | electron microscopy | B, A | — | — |
| 6QVU | CryoEM structure of the human ClC-1 chloride channel, low pH | electron microscopy | B, A | — | 20 (best 0.84) |
| 6QVU | Cryoem structure of the human clc-1 chloride channel, low pH | electron microscopy | B, A | — | — |
| 8WXI | human CLC-1 D136G delayed rectification | electron microscopy | A, B | SCN | 12 (best 0.76) |
| P35523 | AlphaFold monomer V2.0 prediction for chloride channel protein 1 (P35523) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8WXI chain A against the predicted model P35523: TM-score 0.98, RMSD 1.42 Å
- 8WXI chain B against the predicted model P35523: TM-score 0.98, RMSD 1.42 Å
- 6COY chain A against the predicted model P35523: TM-score 0.98, RMSD 1.32 Å
- 6COY chain B against the predicted model P35523: TM-score 0.98, RMSD 1.32 Å
- 6QV6 chain B against the predicted model P35523: TM-score 0.97, RMSD 1.45 Å
- 6QV6 chain A against the predicted model P35523: TM-score 0.97, RMSD 1.45 Å
- 6QVD chain B against the predicted model P35523: TM-score 0.94, RMSD 2.41 Å
- 6QVD chain B against the predicted model P35523: TM-score 0.94, RMSD 2.41 Å
- 6QVD chain A against the predicted model P35523: TM-score 0.94, RMSD 2.41 Å
- 6QVD chain A against the predicted model P35523: TM-score 0.94, RMSD 2.41 Å
Elsewhere
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