UniProt P28827
Receptor-type tyrosine-protein phosphatase mu (P28827)
Receptor-type tyrosine-protein phosphatase mu (UniProt P28827), EC 3.1.3.48: 8 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P28827
- Protein
- Receptor-type tyrosine-protein phosphatase mu
- EC
- 3.1.3.48
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 27 · 3 records with a druggable one
Structures
9 records of P28827 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1RPM | Human receptor protein tyrosine phosphatase mu, domain 1 | x-ray diffraction | A, B | — | — |
| 1RPM | Human receptor protein tyrosine phosphatase mu, domain 1 | x-ray diffraction | A, B | — | — |
| 2C9A | Crystal structure of the MAM-Ig module of receptor protein tyrosine phosphatase mu | x-ray diffraction | A | — | — |
| 2C9A | Crystal structure of the mam-ig module of receptor protein tyrosine phosphatase mu | x-ray diffraction | A | — | — |
| 2V5Y | Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain | x-ray diffraction | A | — | — |
| 2V5Y | Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain | x-ray diffraction | A | — | — |
| 8A16 | Human PTPRM domains FN3-4, in spacegroup P212121 | x-ray diffraction | A, B | NAG, FUC | 1 (best 0.71) |
| 8A17 | Human PTPRM domains FN3-4, in spacegroup P3221 | x-ray diffraction | A, B, C, D | NAG, FUC | 14 (best 0.71) |
| P28827 | AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase mu (P28827) | predicted | A | — | 12 (best 0.84) |
Ligands
Experiment against prediction
- 1RPM chain A against the predicted model P28827: TM-score 0.99, RMSD 0.94 Å
- 1RPM chain A against the predicted model P28827: TM-score 0.99, RMSD 0.94 Å
- 2C9A chain A against the predicted model P28827: TM-score 0.96, RMSD 1.27 Å
- 2C9A chain A against the predicted model P28827: TM-score 0.96, RMSD 1.27 Å
- 8A17 chain B against the predicted model P28827: TM-score 0.94, RMSD 1.61 Å
- 8A16 chain A against the predicted model P28827: TM-score 0.93, RMSD 1.54 Å
- 8A16 chain B against the predicted model P28827: TM-score 0.93, RMSD 1.69 Å
- 8A17 chain C against the predicted model P28827: TM-score 0.93, RMSD 1.73 Å
- 8A17 chain D against the predicted model P28827: TM-score 0.93, RMSD 1.71 Å
- 8A17 chain A against the predicted model P28827: TM-score 0.93, RMSD 1.75 Å
Elsewhere
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