Crystal structure of the mam-ig module of receptor protein tyrosine phosphatase mu

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 47% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A
• MAN · alpha-D-mannopyranose · sugar · 2 copies
• FUC · alpha-L-fucopyranose · sugar
• NA · Sodium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide, 3 glycan, 3 modified (disulfide, N-glycosylation, engineered).

Compared structures

• 2C9A · Crystal structure of the MAM-Ig module of receptor protein tyrosine phosphatase mu · the same entry in another collection · chain A against A, TM-score 1.00
• P28827 · AlphaFold monomer V2.0 prediction for receptor-type tyrosine-protein phosphatase mu… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P28827
• Elsewhere: RCSB PDB 2C9A · PDBe 2C9A · UniProt P28827