UniProt P27449
V-type proton ATPase 16 kDa proteolipid subunit (P27449)
V-type proton ATPase 16 kDa proteolipid subunit (UniProt P27449): 11 experimental structures on GenesisL1, 11 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P27449
- Protein
- V-type proton ATPase 16 kDa proteolipid subunit
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 11
- Pockets
- 33 · 6 records with a druggable one
Structures
11 records of P27449 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WLW | The Vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | GAL, NGA, SIA, MAN, WSS, PTY | 14 (best 0.83) |
| 6WLW | The vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | GAL, NGA, SIA, WSS, PTY, WJS | — |
| 6WM2 | Human V-ATPase in state 1 with SidK and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | GAL, NGA, SIA, MAN, PSF, WJP | 5 (best 0.82) |
| 6WM2 | Human V-ATPase in state 1 with sidk and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | GAL, SIA, WJP, WSS, PTY, WJS | — |
| 6WM3 | Human V-ATPase in state 2 with SidK and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | — | 4 (best 0.83) |
| 6WM3 | Human V-ATPase in state 2 with sidk and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | — | — |
| 6WM4 | Human V-ATPase in state 3 with SidK and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | — | 4 (best 0.84) |
| 6WM4 | Human V-ATPase in state 3 with sidk and ADP | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | — | — |
| 7U4T | Human V-ATPase in state 2 with SidK and mEAK-7 | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8, 9 | — | 3 (best 0.82) |
| 7UNF | CryoEM structure of a mEAK7 bound human V-ATPase complex | electron microscopy | 8, 9, 2, 3, 4, 5, 6, 7, 0 | POV | 3 (best 0.82) |
| P27449 | AlphaFold monomer V2.0 prediction for V-type proton ATPase 16 kda proteolipid subunit (P27449) | — | — | — |
Ligands
- CLR · Cholesterol · in 4 records
- GAL · beta-D-galactopyranose · in 4 records
- PTY · Phosphatidylethanolamine · in 4 records
- SIA · N-acetyl-alpha-neuraminic acid · in 4 records
- WJP · Methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6, 10,14,18-tetraen-1-yl dihydrogen diphosphate · in 4 records
- WJS · (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid · in 4 records
- WSS · tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium · in 4 records
- NGA · 2-acetamido-2-deoxy-beta-D-galactopyranose · in 3 records
- MAN · alpha-D-mannopyranose · in 2 records
- PSF · 1,2-dicaproyl-sn-phosphatidyl-L-serine · in 2 records
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 1 record
Elsewhere
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